Exploiting β‐Lactams‐Induced Lysis and DNA Fragmentation for Rapid Molecular Antimicrobial Susceptibility Testing of Neisseria Gonorrhoeae via Dual‐Digital PCR

Exploiting β‐Lactams‐Induced Lysis and DNA Fragmentation for Rapid Molecular Antimicrobial Susceptibility Testing of Neisseria Gonorrhoeae via Dual‐Digital PCR

Abstract The evolution of antimicrobial resistance (AMR) presents substantial challenges to global medical health systems. Neisseria gonorrhoeae (N. gonorrhoeae), in particular, has developed resistance to all currently available antimicrobials. Addressing this issue necessitates not only discoverin...

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Bibliographic Details
Main Authors: Jiumei Hu, Liben Chen, Pengfei Zhang, Fan‐En Chen, Hui Li, Kuangwen Hsieh, Sixuan Li, Johan H. Melendez, Tza‐Huei Wang
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
antimicrobial resistance
bacterial lysis
DNA fragmentation
microfluidic dual‐digital PCR
Nesseria gonorrhoeae (N. gonorrheoae)
Online Access:https://doi.org/10.1002/advs.202405272
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