Large Brunner’s Gland Hyperplasia with Bleeding: A Case Report

We report a rare case of a large Brunner’s gland hyperplasia (BGH) with severe anemia. A 33-year-old woman was transferred to our hospital with anemia and a duodenal mass. She had a 2-week history of melena and mild shortness of breath. Her hemoglobin level was 4.9 g/dl, and she required a blood tra...

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Main Authors: Yuki Okutomi, Takaharu Kato, Hidetoshi Aizawa, Yuhei Endo, Naoya Kasahara, Fumiaki Watanabe, Hiroshi Noda, Toishiki Rikiyama
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2021/8861308
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author Yuki Okutomi
Takaharu Kato
Hidetoshi Aizawa
Yuhei Endo
Naoya Kasahara
Fumiaki Watanabe
Hiroshi Noda
Toishiki Rikiyama
author_facet Yuki Okutomi
Takaharu Kato
Hidetoshi Aizawa
Yuhei Endo
Naoya Kasahara
Fumiaki Watanabe
Hiroshi Noda
Toishiki Rikiyama
author_sort Yuki Okutomi
collection DOAJ
description We report a rare case of a large Brunner’s gland hyperplasia (BGH) with severe anemia. A 33-year-old woman was transferred to our hospital with anemia and a duodenal mass. She had a 2-week history of melena and mild shortness of breath. Her hemoglobin level was 4.9 g/dl, and she required a blood transfusion. Abdominal computed tomography revealed a 7 cm tumor in the descending duodenum, and duodenoscopy revealed a polyp-like tumor with an ulcer at the duodenal bulb. We decided to perform surgery to prevent further bleeding. Intraoperatively, the tumor stalk was located at the anterior wall of the duodenal bulb; the ampulla was not involved, and we resected the tumor with the wall of the duodenal bulb. The resected tumor measured 7.0×4.0×2.3 cm, and pathologically, the tumor consisted of proliferated Brunner’s glands in a small amount of fibrous stroma. The histological diagnosis was BGH with no malignancy. Most cases of BGH are benign and asymptomatic; however, it is important to be aware that some patients have severe anemia, gastrointestinal obstruction, or malignant potential.
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spelling doaj-art-ebe4fd6a2502464ea633cec7ddbddcd92025-08-20T03:21:18ZengWileyCase Reports in Surgery2090-69002090-69192021-01-01202110.1155/2021/88613088861308Large Brunner’s Gland Hyperplasia with Bleeding: A Case ReportYuki Okutomi0Takaharu Kato1Hidetoshi Aizawa2Yuhei Endo3Naoya Kasahara4Fumiaki Watanabe5Hiroshi Noda6Toishiki Rikiyama7Department of Surgery, Saitama Medical Center, Jichi Medical University, 1-847, Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847, Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847, Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847, Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847, Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847, Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847, Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanDepartment of Surgery, Saitama Medical Center, Jichi Medical University, 1-847, Amanuma-cho, Omiya-ku, Saitama 330-8503, JapanWe report a rare case of a large Brunner’s gland hyperplasia (BGH) with severe anemia. A 33-year-old woman was transferred to our hospital with anemia and a duodenal mass. She had a 2-week history of melena and mild shortness of breath. Her hemoglobin level was 4.9 g/dl, and she required a blood transfusion. Abdominal computed tomography revealed a 7 cm tumor in the descending duodenum, and duodenoscopy revealed a polyp-like tumor with an ulcer at the duodenal bulb. We decided to perform surgery to prevent further bleeding. Intraoperatively, the tumor stalk was located at the anterior wall of the duodenal bulb; the ampulla was not involved, and we resected the tumor with the wall of the duodenal bulb. The resected tumor measured 7.0×4.0×2.3 cm, and pathologically, the tumor consisted of proliferated Brunner’s glands in a small amount of fibrous stroma. The histological diagnosis was BGH with no malignancy. Most cases of BGH are benign and asymptomatic; however, it is important to be aware that some patients have severe anemia, gastrointestinal obstruction, or malignant potential.http://dx.doi.org/10.1155/2021/8861308
spellingShingle Yuki Okutomi
Takaharu Kato
Hidetoshi Aizawa
Yuhei Endo
Naoya Kasahara
Fumiaki Watanabe
Hiroshi Noda
Toishiki Rikiyama
Large Brunner’s Gland Hyperplasia with Bleeding: A Case Report
Case Reports in Surgery
title Large Brunner’s Gland Hyperplasia with Bleeding: A Case Report
title_full Large Brunner’s Gland Hyperplasia with Bleeding: A Case Report
title_fullStr Large Brunner’s Gland Hyperplasia with Bleeding: A Case Report
title_full_unstemmed Large Brunner’s Gland Hyperplasia with Bleeding: A Case Report
title_short Large Brunner’s Gland Hyperplasia with Bleeding: A Case Report
title_sort large brunner s gland hyperplasia with bleeding a case report
url http://dx.doi.org/10.1155/2021/8861308
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