NORMOTHERMIC EXTRACORPORAL PERFUSION IN SITU AS A WAY OF RECOVERY KIDNEY TRANSPLANTS FROM DONORS WITH SUDDEN IRREVERSIBLE CARDIAC ARREST
The potential of donors after cardiac death is actual issue. The crucial point in uncontrolled donors after cardiac death is the warm ischemical time. Definition of the limit of warm ischemic time is was the one task of our work and other one is development of preservation protocol saving quality of...
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Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
2010-06-01
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| Series: | Вестник трансплантологии и искусственных органов |
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| Online Access: | https://journal.transpl.ru/vtio/article/view/292 |
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| author | S. F. Bagnenko A. E. Skvortsov V. N. Poptsov I. V. Loginov A. N. Ananyev O. N. Reznik Y. G. Moysyuk |
| author_facet | S. F. Bagnenko A. E. Skvortsov V. N. Poptsov I. V. Loginov A. N. Ananyev O. N. Reznik Y. G. Moysyuk |
| author_sort | S. F. Bagnenko |
| collection | DOAJ |
| description | The potential of donors after cardiac death is actual issue. The crucial point in uncontrolled donors after cardiac death is the warm ischemical time. Definition of the limit of warm ischemic time is was the one task of our work and other one is development of preservation protocol saving quality of kidneys. There were 6 uncontrolled donors with warm ischemic time from 45 up to 91 minutes in which was adapted extracorporal perfusion device for preservation and restoration of kidneys after ischemical damage. The main attention was paid to the elimination of leucocytes as the main damaging factor from modificated donor’s blood circulating in device. In 6 of such kidneys recipients from 12 were immediately graft function, and to the end of third month the average creatinine was 121,3 ± 28,9 mmol/l. Treatment of ischemically damaged kidneys by normothermic extracorporal perfusion with leucocytes depletion before procurement could consider as challenging protocol and demands further study. |
| format | Article |
| id | doaj-art-ebe18a2c52a1486680a58f9be79205b3 |
| institution | Kabale University |
| issn | 1995-1191 |
| language | Russian |
| publishDate | 2010-06-01 |
| publisher | Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov |
| record_format | Article |
| series | Вестник трансплантологии и искусственных органов |
| spelling | doaj-art-ebe18a2c52a1486680a58f9be79205b32025-08-20T03:44:23ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovВестник трансплантологии и искусственных органов1995-11912010-06-01121616710.15825/1995-1191-2010-1-61-67235NORMOTHERMIC EXTRACORPORAL PERFUSION IN SITU AS A WAY OF RECOVERY KIDNEY TRANSPLANTS FROM DONORS WITH SUDDEN IRREVERSIBLE CARDIAC ARRESTS. F. Bagnenko0A. E. Skvortsov1V. N. Poptsov2I. V. Loginov3A. N. Ananyev4O. N. Reznik5Y. G. Moysyuk6State Research Institute for Emergency named after I.I. Djanelidze, Saint-PetersburgState Research Institute for Emergency named after I.I. Djanelidze, Saint-PetersburgAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowState Research Institute for Emergency named after I.I. Djanelidze, Saint-PetersburgState Research Institute for Emergency named after I.I. Djanelidze, Saint-PetersburgState Research Institute for Emergency named after I.I. Djanelidze, Saint-PetersburgAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowThe potential of donors after cardiac death is actual issue. The crucial point in uncontrolled donors after cardiac death is the warm ischemical time. Definition of the limit of warm ischemic time is was the one task of our work and other one is development of preservation protocol saving quality of kidneys. There were 6 uncontrolled donors with warm ischemic time from 45 up to 91 minutes in which was adapted extracorporal perfusion device for preservation and restoration of kidneys after ischemical damage. The main attention was paid to the elimination of leucocytes as the main damaging factor from modificated donor’s blood circulating in device. In 6 of such kidneys recipients from 12 were immediately graft function, and to the end of third month the average creatinine was 121,3 ± 28,9 mmol/l. Treatment of ischemically damaged kidneys by normothermic extracorporal perfusion with leucocytes depletion before procurement could consider as challenging protocol and demands further study.https://journal.transpl.ru/vtio/article/view/292uncontrolled donors after cardiac deathwarm ischemic timeleucocytes depletion |
| spellingShingle | S. F. Bagnenko A. E. Skvortsov V. N. Poptsov I. V. Loginov A. N. Ananyev O. N. Reznik Y. G. Moysyuk NORMOTHERMIC EXTRACORPORAL PERFUSION IN SITU AS A WAY OF RECOVERY KIDNEY TRANSPLANTS FROM DONORS WITH SUDDEN IRREVERSIBLE CARDIAC ARREST Вестник трансплантологии и искусственных органов uncontrolled donors after cardiac death warm ischemic time leucocytes depletion |
| title | NORMOTHERMIC EXTRACORPORAL PERFUSION IN SITU AS A WAY OF RECOVERY KIDNEY TRANSPLANTS FROM DONORS WITH SUDDEN IRREVERSIBLE CARDIAC ARREST |
| title_full | NORMOTHERMIC EXTRACORPORAL PERFUSION IN SITU AS A WAY OF RECOVERY KIDNEY TRANSPLANTS FROM DONORS WITH SUDDEN IRREVERSIBLE CARDIAC ARREST |
| title_fullStr | NORMOTHERMIC EXTRACORPORAL PERFUSION IN SITU AS A WAY OF RECOVERY KIDNEY TRANSPLANTS FROM DONORS WITH SUDDEN IRREVERSIBLE CARDIAC ARREST |
| title_full_unstemmed | NORMOTHERMIC EXTRACORPORAL PERFUSION IN SITU AS A WAY OF RECOVERY KIDNEY TRANSPLANTS FROM DONORS WITH SUDDEN IRREVERSIBLE CARDIAC ARREST |
| title_short | NORMOTHERMIC EXTRACORPORAL PERFUSION IN SITU AS A WAY OF RECOVERY KIDNEY TRANSPLANTS FROM DONORS WITH SUDDEN IRREVERSIBLE CARDIAC ARREST |
| title_sort | normothermic extracorporal perfusion in situ as a way of recovery kidney transplants from donors with sudden irreversible cardiac arrest |
| topic | uncontrolled donors after cardiac death warm ischemic time leucocytes depletion |
| url | https://journal.transpl.ru/vtio/article/view/292 |
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