Alzheimer’s Disease Detection from Retinal Images Using Machine Learning and Deep Learning Techniques: A Perspective

Alzheimer’s disease (AD) is a neurodegenerative disease that results in a loss of cognitive functions. The early discovery of it can potentially stop or decrease the severity of AD. Extensive research has been conducted to find AD biomarkers. In recent years, due to the development of AI technologie...

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Main Authors: Adilet Uvaliyev, Leanne Lai Hang Chan
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/15/9/4963
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author Adilet Uvaliyev
Leanne Lai Hang Chan
author_facet Adilet Uvaliyev
Leanne Lai Hang Chan
author_sort Adilet Uvaliyev
collection DOAJ
description Alzheimer’s disease (AD) is a neurodegenerative disease that results in a loss of cognitive functions. The early discovery of it can potentially stop or decrease the severity of AD. Extensive research has been conducted to find AD biomarkers. In recent years, due to the development of AI technologies and the ease of obtaining retinal images, various machine learning (ML)- and deep learning (DL)-based methods of identifying AD patients from these images have been proposed. These models are significant as they represent a potential screening tool for AD and a tool for identifying biomarkers from retinal images. This paper reviews the recent progress in this direction. It presents an overview of relevant methods and analyzes their strengths and limitations. Also, it discusses common challenges and possible future directions related to this topic.
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spelling doaj-art-ebdc3d9cabb84236a9bfe8948c58bd842025-08-20T02:24:44ZengMDPI AGApplied Sciences2076-34172025-04-01159496310.3390/app15094963Alzheimer’s Disease Detection from Retinal Images Using Machine Learning and Deep Learning Techniques: A PerspectiveAdilet Uvaliyev0Leanne Lai Hang Chan1Department of Electrical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, ChinaDepartment of Electrical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR, ChinaAlzheimer’s disease (AD) is a neurodegenerative disease that results in a loss of cognitive functions. The early discovery of it can potentially stop or decrease the severity of AD. Extensive research has been conducted to find AD biomarkers. In recent years, due to the development of AI technologies and the ease of obtaining retinal images, various machine learning (ML)- and deep learning (DL)-based methods of identifying AD patients from these images have been proposed. These models are significant as they represent a potential screening tool for AD and a tool for identifying biomarkers from retinal images. This paper reviews the recent progress in this direction. It presents an overview of relevant methods and analyzes their strengths and limitations. Also, it discusses common challenges and possible future directions related to this topic.https://www.mdpi.com/2076-3417/15/9/4963Alzheimer’s diseaseretinal imagesmachine learningdeep learning
spellingShingle Adilet Uvaliyev
Leanne Lai Hang Chan
Alzheimer’s Disease Detection from Retinal Images Using Machine Learning and Deep Learning Techniques: A Perspective
Applied Sciences
Alzheimer’s disease
retinal images
machine learning
deep learning
title Alzheimer’s Disease Detection from Retinal Images Using Machine Learning and Deep Learning Techniques: A Perspective
title_full Alzheimer’s Disease Detection from Retinal Images Using Machine Learning and Deep Learning Techniques: A Perspective
title_fullStr Alzheimer’s Disease Detection from Retinal Images Using Machine Learning and Deep Learning Techniques: A Perspective
title_full_unstemmed Alzheimer’s Disease Detection from Retinal Images Using Machine Learning and Deep Learning Techniques: A Perspective
title_short Alzheimer’s Disease Detection from Retinal Images Using Machine Learning and Deep Learning Techniques: A Perspective
title_sort alzheimer s disease detection from retinal images using machine learning and deep learning techniques a perspective
topic Alzheimer’s disease
retinal images
machine learning
deep learning
url https://www.mdpi.com/2076-3417/15/9/4963
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AT leannelaihangchan alzheimersdiseasedetectionfromretinalimagesusingmachinelearninganddeeplearningtechniquesaperspective