Deducing high-accuracy protein contact-maps from a triplet of coevolutionary matrices through deep residual convolutional networks.

The topology of protein folds can be specified by the inter-residue contact-maps and accurate contact-map prediction can help ab initio structure folding. We developed TripletRes to deduce protein contact-maps from discretized distance profiles by end-to-end training of deep residual neural-networks...

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Bibliographic Details
Main Authors: Yang Li, Chengxin Zhang, Eric W Bell, Wei Zheng, Xiaogen Zhou, Dong-Jun Yu, Yang Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1008865&type=printable
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