The potential shared role of inflammation in insulin resistance and schizophrenia: A bidirectional two-sample mendelian randomization study.

The potential shared role of inflammation in insulin resistance and schizophrenia: A bidirectional two-sample mendelian randomization study.

<h4>Background</h4>Insulin resistance predisposes to cardiometabolic disorders, which are commonly comorbid with schizophrenia and are key contributors to the significant excess mortality in schizophrenia. Mechanisms for the comorbidity remain unclear, but observational studies have impl...

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Bibliographic Details
Main Authors: Benjamin I Perry, Stephen Burgess, Hannah J Jones, Stan Zammit, Rachel Upthegrove, Amy M Mason, Felix R Day, Claudia Langenberg, Nicholas J Wareham, Peter B Jones, Golam M Khandaker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1003455&type=printable
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