A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment

Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along...

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Main Authors: Shahzad Ahmad, Mahmoud Abdelghany, Curtis Goldblatt, Owen Stark, Nicholas Masciotra
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2014/968926
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author Shahzad Ahmad
Mahmoud Abdelghany
Curtis Goldblatt
Owen Stark
Nicholas Masciotra
author_facet Shahzad Ahmad
Mahmoud Abdelghany
Curtis Goldblatt
Owen Stark
Nicholas Masciotra
author_sort Shahzad Ahmad
collection DOAJ
description Primary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along with immunoreactivity to S-100 and human melanoma black-45 (HMB-45) confirmed the diagnosis. The patient was treated with laryngectomy followed by radiotherapy. Five years following surgical treatment, she continues to be asymptomatic. To our knowledge, there is only one reported case of primary malignant melanoma of subglottic mucosa in the medical literatures.
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series Case Reports in Oncological Medicine
spelling doaj-art-ebcf63e6d7af4bb994f39c948556a08a2025-08-20T03:21:18ZengWileyCase Reports in Oncological Medicine2090-67062090-67142014-01-01201410.1155/2014/968926968926A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical TreatmentShahzad Ahmad0Mahmoud Abdelghany1Curtis Goldblatt2Owen Stark3Nicholas Masciotra4Department of Medicine, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USADepartment of Medicine, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USADepartment of Anatomic and Clinical Pathology, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USADepartment of Radiology, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USADepartment of Otolaryngology, Conemaugh Memorial Medical Center, Johnstown, PA 15905, USAPrimary subglottic malignant melanoma is a very rare and underdiagnosed neoplasm. We are reporting a case of primary malignant melanoma of subglottic mucosa in a 78-year-old woman who presented to our hospital with shortness of breath and hoarseness of voice. Laryngoscopy and excisional biopsy along with immunoreactivity to S-100 and human melanoma black-45 (HMB-45) confirmed the diagnosis. The patient was treated with laryngectomy followed by radiotherapy. Five years following surgical treatment, she continues to be asymptomatic. To our knowledge, there is only one reported case of primary malignant melanoma of subglottic mucosa in the medical literatures.http://dx.doi.org/10.1155/2014/968926
spellingShingle Shahzad Ahmad
Mahmoud Abdelghany
Curtis Goldblatt
Owen Stark
Nicholas Masciotra
A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
Case Reports in Oncological Medicine
title A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title_full A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title_fullStr A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title_full_unstemmed A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title_short A Case of Primary Subglottic Malignant Melanoma with a Successful Surgical Treatment
title_sort case of primary subglottic malignant melanoma with a successful surgical treatment
url http://dx.doi.org/10.1155/2014/968926
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