From the emergency department to veno-venous ECMO- a case of refractory hypoxia
Background: A known rare side effect of naloxone administration is non-cardiac pulmonary edema. There have been multiple proposed mechanisms for this, the most accepted one being a catecholamine surge causing physiologic changes favoring the development of pulmonary edema. The literature is sparse o...
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Elsevier
2025-06-01
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| Series: | JEM Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2773232025000379 |
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| author | Joshua Fuller Cameron Harrison |
| author_facet | Joshua Fuller Cameron Harrison |
| author_sort | Joshua Fuller |
| collection | DOAJ |
| description | Background: A known rare side effect of naloxone administration is non-cardiac pulmonary edema. There have been multiple proposed mechanisms for this, the most accepted one being a catecholamine surge causing physiologic changes favoring the development of pulmonary edema. The literature is sparse on this clinical entity, mostly consisting of case reports and a case series. Case report: Here we present a case of a young male who presents with refractory hypoxia and shock requiring emergent Extracorporeal Membrane Oxygenation (ECMO) consultation and cannulation for veno-venous ECMO(VV-ECMO) from the emergency department. The patient responded well and was decannulated and extubated within 50 hours and ultimately discharged on hospital day 6. Why should an emergency physician be aware of this: This would be a rare publication of VV-ECMO being used emergently for hypoxic respiratory failure secondary to naloxone-induced pulmonary edema compounded by subsequent aspiration in the Emergency Department. |
| format | Article |
| id | doaj-art-ebc82ddd4cd84045989c0b6dee592eaa |
| institution | DOAJ |
| issn | 2773-2320 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JEM Reports |
| spelling | doaj-art-ebc82ddd4cd84045989c0b6dee592eaa2025-08-20T03:22:09ZengElsevierJEM Reports2773-23202025-06-014210017310.1016/j.jemrpt.2025.100173From the emergency department to veno-venous ECMO- a case of refractory hypoxiaJoshua Fuller0Cameron Harrison1Corresponding author. University of Texas Health Science Center at San Antonio.; University of Texas Health Science Center at San AntonioUniversity of Texas Health Science Center at San AntonioBackground: A known rare side effect of naloxone administration is non-cardiac pulmonary edema. There have been multiple proposed mechanisms for this, the most accepted one being a catecholamine surge causing physiologic changes favoring the development of pulmonary edema. The literature is sparse on this clinical entity, mostly consisting of case reports and a case series. Case report: Here we present a case of a young male who presents with refractory hypoxia and shock requiring emergent Extracorporeal Membrane Oxygenation (ECMO) consultation and cannulation for veno-venous ECMO(VV-ECMO) from the emergency department. The patient responded well and was decannulated and extubated within 50 hours and ultimately discharged on hospital day 6. Why should an emergency physician be aware of this: This would be a rare publication of VV-ECMO being used emergently for hypoxic respiratory failure secondary to naloxone-induced pulmonary edema compounded by subsequent aspiration in the Emergency Department.http://www.sciencedirect.com/science/article/pii/S2773232025000379Veno-venous ECMONaloxonePulmonary edemaRefractory hypoxia |
| spellingShingle | Joshua Fuller Cameron Harrison From the emergency department to veno-venous ECMO- a case of refractory hypoxia JEM Reports Veno-venous ECMO Naloxone Pulmonary edema Refractory hypoxia |
| title | From the emergency department to veno-venous ECMO- a case of refractory hypoxia |
| title_full | From the emergency department to veno-venous ECMO- a case of refractory hypoxia |
| title_fullStr | From the emergency department to veno-venous ECMO- a case of refractory hypoxia |
| title_full_unstemmed | From the emergency department to veno-venous ECMO- a case of refractory hypoxia |
| title_short | From the emergency department to veno-venous ECMO- a case of refractory hypoxia |
| title_sort | from the emergency department to veno venous ecmo a case of refractory hypoxia |
| topic | Veno-venous ECMO Naloxone Pulmonary edema Refractory hypoxia |
| url | http://www.sciencedirect.com/science/article/pii/S2773232025000379 |
| work_keys_str_mv | AT joshuafuller fromtheemergencydepartmenttovenovenousecmoacaseofrefractoryhypoxia AT cameronharrison fromtheemergencydepartmenttovenovenousecmoacaseofrefractoryhypoxia |