Biotechnological tools boost the functional diversity of DNA-based data storage systems

DNA-based data storage has emerged as a groundbreaking solution to the growing demand for efficient, high-density, and long-term data storage. It is attracting many researchers’ attention, who are implementing functions such as random access, searching, and data operations apart from the existing ca...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaoyuan Xu, Wen Wang, Zhi Ping
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025000297
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1823856867920576512
author Xiaoyuan Xu
Wen Wang
Zhi Ping
author_facet Xiaoyuan Xu
Wen Wang
Zhi Ping
author_sort Xiaoyuan Xu
collection DOAJ
description DNA-based data storage has emerged as a groundbreaking solution to the growing demand for efficient, high-density, and long-term data storage. It is attracting many researchers’ attention, who are implementing functions such as random access, searching, and data operations apart from the existing capabilities, including reading and writing. We summarize the recent progress of how biotechnological tools, based on sequence specificity, encapsulation, and high-dimensional structures of DNA molecules, facilitate the implementation of various functions. The limitations of using biochemical reactions that hinder the development of more precise and efficient information storage systems are also discussed. Future advancements in molecular biology and nanotechnology are expected to improve the architecture, scalability, and efficiency of DNA storage, positioning it as a sustainable and dynamic alternative to conventional data storage systems.
format Article
id doaj-art-ebbe0430a2b54eb2b170afc75dc847cf
institution Kabale University
issn 2001-0370
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series Computational and Structural Biotechnology Journal
spelling doaj-art-ebbe0430a2b54eb2b170afc75dc847cf2025-02-12T05:30:58ZengElsevierComputational and Structural Biotechnology Journal2001-03702025-01-0127624630Biotechnological tools boost the functional diversity of DNA-based data storage systemsXiaoyuan Xu0Wen Wang1Zhi Ping2School of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, ChinaBGI Research, Beijing 100101, China; BGI Research, Shenzhen 518083, ChinaSchool of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, China; BGI Research, Beijing 100101, China; BGI Research, Shenzhen 518083, China; Corresponding author at: School of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, China.DNA-based data storage has emerged as a groundbreaking solution to the growing demand for efficient, high-density, and long-term data storage. It is attracting many researchers’ attention, who are implementing functions such as random access, searching, and data operations apart from the existing capabilities, including reading and writing. We summarize the recent progress of how biotechnological tools, based on sequence specificity, encapsulation, and high-dimensional structures of DNA molecules, facilitate the implementation of various functions. The limitations of using biochemical reactions that hinder the development of more precise and efficient information storage systems are also discussed. Future advancements in molecular biology and nanotechnology are expected to improve the architecture, scalability, and efficiency of DNA storage, positioning it as a sustainable and dynamic alternative to conventional data storage systems.http://www.sciencedirect.com/science/article/pii/S2001037025000297DNA data storageDNA nanostructureDNA storage system
spellingShingle Xiaoyuan Xu
Wen Wang
Zhi Ping
Biotechnological tools boost the functional diversity of DNA-based data storage systems
Computational and Structural Biotechnology Journal
DNA data storage
DNA nanostructure
DNA storage system
title Biotechnological tools boost the functional diversity of DNA-based data storage systems
title_full Biotechnological tools boost the functional diversity of DNA-based data storage systems
title_fullStr Biotechnological tools boost the functional diversity of DNA-based data storage systems
title_full_unstemmed Biotechnological tools boost the functional diversity of DNA-based data storage systems
title_short Biotechnological tools boost the functional diversity of DNA-based data storage systems
title_sort biotechnological tools boost the functional diversity of dna based data storage systems
topic DNA data storage
DNA nanostructure
DNA storage system
url http://www.sciencedirect.com/science/article/pii/S2001037025000297
work_keys_str_mv AT xiaoyuanxu biotechnologicaltoolsboostthefunctionaldiversityofdnabaseddatastoragesystems
AT wenwang biotechnologicaltoolsboostthefunctionaldiversityofdnabaseddatastoragesystems
AT zhiping biotechnologicaltoolsboostthefunctionaldiversityofdnabaseddatastoragesystems