Enhancing Male Fertility Through Nutrition: The Role of L-Carnitine in Asthenozoospermic Patients

Infertility, which affects millions worldwide, often involves male factors such as asthenozoospermia, a condition marked by reduced sperm motility. While lifestyle and environmental factors are major contributors, nutritional interventions offer an effective, non-invasive approach to treatment. This...

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Main Authors: Jafar Shaikh, Akash More, Namrata Anjankar, Nancy Nair, Sanket S. Mahajan, Neha Nawale
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-05-01
Series:Journal of Pharmacy and Bioallied Sciences
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Online Access:https://journals.lww.com/10.4103/jpbs.jpbs_94_25
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Summary:Infertility, which affects millions worldwide, often involves male factors such as asthenozoospermia, a condition marked by reduced sperm motility. While lifestyle and environmental factors are major contributors, nutritional interventions offer an effective, non-invasive approach to treatment. This case report examines the effects of L-carnitine supplementation on male infertility in a 37-year-old patient with a six-year history of primary infertility. The patient followed a three-month protocol that included 3000 mg of L-carnitine daily, dietary changes rich in antioxidants, and lifestyle modifications. Initial semen analysis revealed significant deficiencies, including progressive motility of 15% and a sperm count of 25 million/mL. After the intervention, notable improvements were observed: progressive motility increased to 50%, sperm count rose to 49 million/mL, and normal morphology improved from 3% to 7%. These results highlight the role of L-carnitine in supporting sperm mitochondrial function, reducing oxidative stress, and improving key fertility parameters. The findings are consistent with existing research demonstrating the potential of L-carnitine as a treatment for male infertility. This report underscores the value of individualized nutritional and supplementation strategies in enhancing reproductive health and suggests L-carnitine as a safe and effective option for treating asthenozoospermia.
ISSN:0976-4879
0975-7406