A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis
Abstract Background This study sought to investigate the prevalence, correlates, and network structure of the manifested symptoms in gambling disorder (GD) among methamphetamine (MA) use disorder (MUD) patients in China. Methods We interviewed 1069 patients using the Semi-Structured Assessment for D...
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BMC
2025-03-01
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| Series: | Annals of General Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12991-025-00546-0 |
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| author | Pu Peng Yuzhu Hao Xiaojie Zhang Yuejiao Ma Xuebing Liu Danlin Shen Wenwen Shen Bin Zhao Dongxiao Li Sarah E. Beck Yaira Z. Nunez Marc N. Potenza Joel Gelernter Tieqiao Liu Bao-Zhu Yang |
| author_facet | Pu Peng Yuzhu Hao Xiaojie Zhang Yuejiao Ma Xuebing Liu Danlin Shen Wenwen Shen Bin Zhao Dongxiao Li Sarah E. Beck Yaira Z. Nunez Marc N. Potenza Joel Gelernter Tieqiao Liu Bao-Zhu Yang |
| author_sort | Pu Peng |
| collection | DOAJ |
| description | Abstract Background This study sought to investigate the prevalence, correlates, and network structure of the manifested symptoms in gambling disorder (GD) among methamphetamine (MA) use disorder (MUD) patients in China. Methods We interviewed 1069 patients using the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA), Chinese version. Besides MA and other substance use disorders, GD was also ascertained by SSADDA. Other psychiatric diagnoses were ascertained, including major depressive episodes (MDEs), antisocial personality disorder, suicide and self-harm, and environmental factors, including childhood experiences. Results Of 1069 participants, 711 met the DSM-5 diagnostic criteria for MUD. Among the 711 participants with MUD, 52.3% met DSM-5 diagnostic criteria for GD. We found that alcohol use together with MA, childhood violent experiences, MDEs, severe MUD, and gambling duration significantly differed between MUD participants with and without GD. In the GD-MUD network, the central symptoms were gambling preoccupation (GD1), giving up important activities (MUD6), financial trouble (GD9), and MA tolerance (MUD5). MA tolerance (MUD5) also served as a bridge symptom across the network, exhibiting substantial associations with gambling preoccupation (GD1). Conclusion GD is prevalent among individuals in treatment for MUD in China. Network analysis suggests that gambling preoccupation and MA tolerance represent central features, and that MA tolerance serves as a bridge across GD and MUD. |
| format | Article |
| id | doaj-art-ebb14886593e4be48d7b2d7229d60185 |
| institution | DOAJ |
| issn | 1744-859X |
| language | English |
| publishDate | 2025-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Annals of General Psychiatry |
| spelling | doaj-art-ebb14886593e4be48d7b2d7229d601852025-08-20T03:05:46ZengBMCAnnals of General Psychiatry1744-859X2025-03-0124111310.1186/s12991-025-00546-0A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysisPu Peng0Yuzhu Hao1Xiaojie Zhang2Yuejiao Ma3Xuebing Liu4Danlin Shen5Wenwen Shen6Bin Zhao7Dongxiao Li8Sarah E. Beck9Yaira Z. Nunez10Marc N. Potenza11Joel Gelernter12Tieqiao Liu13Bao-Zhu Yang14Department of Psychiatry, Sir Run Run Shaw Hospital, Zhejiang University School of MedicineDepartment of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South UniversityDepartment of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South UniversityDepartment of Child Psychiatry of Shenzhen Kangning Hospital, Shenzhen Mental Health Center, School of Mental Health, Shenzhen UniversityNinth Clinical School, Tongji Medical College, Wuhan Mental Health Center, Huazhong University of Science and TechnologyMental Health Center, West China Hospital, Sichuan UniversityLaboratory of Behavioral Neuroscience, Ningbo Kangning Hospital, Ningbo Institute of Microcirculation and Henbane, School of Medicine, Ningbo UniversityXinxiang Key Laboratory for Forensic Toxicology, School of Forensic Medicine, Xinxiang Medical UniversityPingtang Compulsory Isolation Detoxification Institute in Hunan ProvinceDepartment of Psychiatry, Yale University School of MedicineDepartment of Psychiatry, Yale University School of MedicineDepartment of Psychiatry, Yale University School of MedicineDepartment of Psychiatry, Yale University School of MedicineDepartment of Psychiatry, National Clinical Research Center for Mental Disorders, and National Center for Mental Disorders, The Second Xiangya Hospital of Central South UniversityDepartment of Psychiatry, Yale University School of MedicineAbstract Background This study sought to investigate the prevalence, correlates, and network structure of the manifested symptoms in gambling disorder (GD) among methamphetamine (MA) use disorder (MUD) patients in China. Methods We interviewed 1069 patients using the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA), Chinese version. Besides MA and other substance use disorders, GD was also ascertained by SSADDA. Other psychiatric diagnoses were ascertained, including major depressive episodes (MDEs), antisocial personality disorder, suicide and self-harm, and environmental factors, including childhood experiences. Results Of 1069 participants, 711 met the DSM-5 diagnostic criteria for MUD. Among the 711 participants with MUD, 52.3% met DSM-5 diagnostic criteria for GD. We found that alcohol use together with MA, childhood violent experiences, MDEs, severe MUD, and gambling duration significantly differed between MUD participants with and without GD. In the GD-MUD network, the central symptoms were gambling preoccupation (GD1), giving up important activities (MUD6), financial trouble (GD9), and MA tolerance (MUD5). MA tolerance (MUD5) also served as a bridge symptom across the network, exhibiting substantial associations with gambling preoccupation (GD1). Conclusion GD is prevalent among individuals in treatment for MUD in China. Network analysis suggests that gambling preoccupation and MA tolerance represent central features, and that MA tolerance serves as a bridge across GD and MUD.https://doi.org/10.1186/s12991-025-00546-0Addictive behaviorsGambling disorderMethamphetamine use disorderMajor depressive episodeAntisocial personality disorderNetwork analysis |
| spellingShingle | Pu Peng Yuzhu Hao Xiaojie Zhang Yuejiao Ma Xuebing Liu Danlin Shen Wenwen Shen Bin Zhao Dongxiao Li Sarah E. Beck Yaira Z. Nunez Marc N. Potenza Joel Gelernter Tieqiao Liu Bao-Zhu Yang A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis Annals of General Psychiatry Addictive behaviors Gambling disorder Methamphetamine use disorder Major depressive episode Antisocial personality disorder Network analysis |
| title | A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis |
| title_full | A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis |
| title_fullStr | A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis |
| title_full_unstemmed | A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis |
| title_short | A multicenter cross-sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers: prevalence, correlates, and network analysis |
| title_sort | multicenter cross sectional study of gambling disorder among patients with methamphetamine use disorder in drug rehabilitation centers prevalence correlates and network analysis |
| topic | Addictive behaviors Gambling disorder Methamphetamine use disorder Major depressive episode Antisocial personality disorder Network analysis |
| url | https://doi.org/10.1186/s12991-025-00546-0 |
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