A symbiotic mosquito‐gut bacterium for flavivirus control
Abstract Dengue virus (DENV) and Zika virus (ZIKV) have emerged as major global public health challenges, causing numerous infections and fatalities each year. However, current measures, including vaccines and treatments, are often limited or ineffective. This highlights the urgent need for novel pr...
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| Format: | Article |
| Language: | English |
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Wiley
2024-12-01
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| Series: | Clinical and Translational Medicine |
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| Online Access: | https://doi.org/10.1002/ctm2.70087 |
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| author | Jinglin Wang Yibin Zhu Jun Leng Yulin Yuan Yingyi Cao Gong Cheng Xueshan Xia |
| author_facet | Jinglin Wang Yibin Zhu Jun Leng Yulin Yuan Yingyi Cao Gong Cheng Xueshan Xia |
| author_sort | Jinglin Wang |
| collection | DOAJ |
| description | Abstract Dengue virus (DENV) and Zika virus (ZIKV) have emerged as major global public health challenges, causing numerous infections and fatalities each year. However, current measures, including vaccines and treatments, are often limited or ineffective. This highlights the urgent need for novel preventive strategies to control the spread of key mosquito‐borne viruses like DENV and ZIKV. In a recent study published in Science, Zhang et al. isolated a bacterium named Rosenbergiella_YN46 from the gut of field‐caught Aedes albopictus mosquitoes in Yunnan Province, China. This commentary reviews their findings, published on April 19, 2024, which describe the symbiotic bacterium Rosenbergiella_YN46 and its ability to block flavivirus transmission, including both DENV and ZIKV. The bacterium shows promising potential for future dengue fever prevention and provides valuable insights into a novel biological approach for controlling mosquito‐borne viral diseases. |
| format | Article |
| id | doaj-art-ebaa8c81b1f44a4f98e63c6875dd7443 |
| institution | Kabale University |
| issn | 2001-1326 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Translational Medicine |
| spelling | doaj-art-ebaa8c81b1f44a4f98e63c6875dd74432025-01-30T03:56:54ZengWileyClinical and Translational Medicine2001-13262024-12-011412n/an/a10.1002/ctm2.70087A symbiotic mosquito‐gut bacterium for flavivirus controlJinglin Wang0Yibin Zhu1Jun Leng2Yulin Yuan3Yingyi Cao4Gong Cheng5Xueshan Xia6Yunnan Key Laboratory of Cross‐Border Infectious Disease Controlling and Novel Drug Development (Under construction) & Yunnan Provincial Key Laboratory of Public Health and Biosafety School of Public Health, Kunming Medical University Kunming ChinaNew Cornerstone Science Laboratory, Tsinghua University‐Peking University Joint Center for Life Sciences School of Basic Medical Sciences, Tsinghua University Beijing ChinaYunnan Key Laboratory of Cross‐Border Infectious Disease Controlling and Novel Drug Development (Under construction) & Yunnan Provincial Key Laboratory of Public Health and Biosafety School of Public Health, Kunming Medical University Kunming ChinaNew Cornerstone Science Laboratory, Tsinghua University‐Peking University Joint Center for Life Sciences School of Basic Medical Sciences, Tsinghua University Beijing ChinaNew Cornerstone Science Laboratory, Tsinghua University‐Peking University Joint Center for Life Sciences School of Basic Medical Sciences, Tsinghua University Beijing ChinaNew Cornerstone Science Laboratory, Tsinghua University‐Peking University Joint Center for Life Sciences School of Basic Medical Sciences, Tsinghua University Beijing ChinaYunnan Key Laboratory of Cross‐Border Infectious Disease Controlling and Novel Drug Development (Under construction) & Yunnan Provincial Key Laboratory of Public Health and Biosafety School of Public Health, Kunming Medical University Kunming ChinaAbstract Dengue virus (DENV) and Zika virus (ZIKV) have emerged as major global public health challenges, causing numerous infections and fatalities each year. However, current measures, including vaccines and treatments, are often limited or ineffective. This highlights the urgent need for novel preventive strategies to control the spread of key mosquito‐borne viruses like DENV and ZIKV. In a recent study published in Science, Zhang et al. isolated a bacterium named Rosenbergiella_YN46 from the gut of field‐caught Aedes albopictus mosquitoes in Yunnan Province, China. This commentary reviews their findings, published on April 19, 2024, which describe the symbiotic bacterium Rosenbergiella_YN46 and its ability to block flavivirus transmission, including both DENV and ZIKV. The bacterium shows promising potential for future dengue fever prevention and provides valuable insights into a novel biological approach for controlling mosquito‐borne viral diseases.https://doi.org/10.1002/ctm2.70087controldengue virussymbiotic mosquito‐gut bacteriumZika virus |
| spellingShingle | Jinglin Wang Yibin Zhu Jun Leng Yulin Yuan Yingyi Cao Gong Cheng Xueshan Xia A symbiotic mosquito‐gut bacterium for flavivirus control Clinical and Translational Medicine control dengue virus symbiotic mosquito‐gut bacterium Zika virus |
| title | A symbiotic mosquito‐gut bacterium for flavivirus control |
| title_full | A symbiotic mosquito‐gut bacterium for flavivirus control |
| title_fullStr | A symbiotic mosquito‐gut bacterium for flavivirus control |
| title_full_unstemmed | A symbiotic mosquito‐gut bacterium for flavivirus control |
| title_short | A symbiotic mosquito‐gut bacterium for flavivirus control |
| title_sort | symbiotic mosquito gut bacterium for flavivirus control |
| topic | control dengue virus symbiotic mosquito‐gut bacterium Zika virus |
| url | https://doi.org/10.1002/ctm2.70087 |
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