Abiotrophia defectiva bacterial endocarditis complicated by an infective intracranial mycotic aneurysm – The need for aggressive odontogenic source control
Abiotrophia defectiva or nutritionally variant streptococci (NVS) was first described in 1961 as a rare cause of infectious endocarditis (IE). It is distinct to the Streptococcus genus, pleomorphic, and demonstrates variable Gram-staining characteristics due to poor growth in culture media requiring...
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Elsevier
2022-09-01
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| Series: | Journal of Oral Biology and Craniofacial Research |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2212426822001129 |
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| author | Dong Tony Cheng Paul Mercedes Kim Thomas Young Dimitrios Nikolarakos |
| author_facet | Dong Tony Cheng Paul Mercedes Kim Thomas Young Dimitrios Nikolarakos |
| author_sort | Dong Tony Cheng |
| collection | DOAJ |
| description | Abiotrophia defectiva or nutritionally variant streptococci (NVS) was first described in 1961 as a rare cause of infectious endocarditis (IE). It is distinct to the Streptococcus genus, pleomorphic, and demonstrates variable Gram-staining characteristics due to poor growth in culture media requiring extended incubation or 16S rRNA sequencing in culture negative situations.1 NVS has also been implicated in the pathogenesis of culture-negative endocarditis. In comparison with other causes of endocarditis, it has the ability to secrete exopolysaccharide and adheres to fibronectin in the extracellular matrix of endovascular structures.2 NVS is associated with significant morbidity and mortality, higher rates of multisystem complications ranging from pancreatic abscess, intracranial aneurysms, osteomyelitis, and valvular destruction, despite sensitivity to antibiotics. |
| format | Article |
| id | doaj-art-eba9b09d095c4e0a9cc9e0c2616d036f |
| institution | OA Journals |
| issn | 2212-4268 |
| language | English |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Oral Biology and Craniofacial Research |
| spelling | doaj-art-eba9b09d095c4e0a9cc9e0c2616d036f2025-08-20T02:01:57ZengElsevierJournal of Oral Biology and Craniofacial Research2212-42682022-09-0112571371510.1016/j.jobcr.2022.08.021Abiotrophia defectiva bacterial endocarditis complicated by an infective intracranial mycotic aneurysm – The need for aggressive odontogenic source controlDong Tony Cheng0Paul Mercedes Kim1Thomas Young2Dimitrios Nikolarakos3Corresponding author.; Department of Oral and Maxillofacial Surgery, Gold Coast University Hospital, 1 Hospital Blvd, Southport, QLD, 4215, AustraliaDepartment of Oral and Maxillofacial Surgery, Gold Coast University Hospital, 1 Hospital Blvd, Southport, QLD, 4215, AustraliaDepartment of Oral and Maxillofacial Surgery, Gold Coast University Hospital, 1 Hospital Blvd, Southport, QLD, 4215, AustraliaDepartment of Oral and Maxillofacial Surgery, Gold Coast University Hospital, 1 Hospital Blvd, Southport, QLD, 4215, AustraliaAbiotrophia defectiva or nutritionally variant streptococci (NVS) was first described in 1961 as a rare cause of infectious endocarditis (IE). It is distinct to the Streptococcus genus, pleomorphic, and demonstrates variable Gram-staining characteristics due to poor growth in culture media requiring extended incubation or 16S rRNA sequencing in culture negative situations.1 NVS has also been implicated in the pathogenesis of culture-negative endocarditis. In comparison with other causes of endocarditis, it has the ability to secrete exopolysaccharide and adheres to fibronectin in the extracellular matrix of endovascular structures.2 NVS is associated with significant morbidity and mortality, higher rates of multisystem complications ranging from pancreatic abscess, intracranial aneurysms, osteomyelitis, and valvular destruction, despite sensitivity to antibiotics.http://www.sciencedirect.com/science/article/pii/S2212426822001129Abiotrophia defectivaEndocarditisIntracranialMycotic aneurysmOdontogenic |
| spellingShingle | Dong Tony Cheng Paul Mercedes Kim Thomas Young Dimitrios Nikolarakos Abiotrophia defectiva bacterial endocarditis complicated by an infective intracranial mycotic aneurysm – The need for aggressive odontogenic source control Journal of Oral Biology and Craniofacial Research Abiotrophia defectiva Endocarditis Intracranial Mycotic aneurysm Odontogenic |
| title | Abiotrophia defectiva bacterial endocarditis complicated by an infective intracranial mycotic aneurysm – The need for aggressive odontogenic source control |
| title_full | Abiotrophia defectiva bacterial endocarditis complicated by an infective intracranial mycotic aneurysm – The need for aggressive odontogenic source control |
| title_fullStr | Abiotrophia defectiva bacterial endocarditis complicated by an infective intracranial mycotic aneurysm – The need for aggressive odontogenic source control |
| title_full_unstemmed | Abiotrophia defectiva bacterial endocarditis complicated by an infective intracranial mycotic aneurysm – The need for aggressive odontogenic source control |
| title_short | Abiotrophia defectiva bacterial endocarditis complicated by an infective intracranial mycotic aneurysm – The need for aggressive odontogenic source control |
| title_sort | abiotrophia defectiva bacterial endocarditis complicated by an infective intracranial mycotic aneurysm the need for aggressive odontogenic source control |
| topic | Abiotrophia defectiva Endocarditis Intracranial Mycotic aneurysm Odontogenic |
| url | http://www.sciencedirect.com/science/article/pii/S2212426822001129 |
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