How to solve the problem of drug choice within the same class from the standpoint of evidence-based medicine?

The question of the possibility of the most effective drug choosing within one class from the standpoint of evidence-based medicine is considered in the article. Drugs belonging to the same class may have both great similarities and significant differences. This is demonstrated by the example of dif...

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Main Author: S. Yu. Martsevich
Format: Article
Language:English
Published: Столичная издательская компания 2019-05-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/1925
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author S. Yu. Martsevich
author_facet S. Yu. Martsevich
author_sort S. Yu. Martsevich
collection DOAJ
description The question of the possibility of the most effective drug choosing within one class from the standpoint of evidence-based medicine is considered in the article. Drugs belonging to the same class may have both great similarities and significant differences. This is demonstrated by the example of different classes of drugs (beta-blockers, angiotensin-converting enzyme inhibitors, and new oral anticoagulants). The choice of the most effective (from the standpoint of evidence-based medicine) is impossible if there are no direct comparisons in randomized controlled studies between drugs of the same class that have demonstrated their effectiveness separately. Analysis of observational studies (large databases, registers) to identify the most effective drug in a class cannot be used to solve the problem of the superiority of a drug within a class.
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institution Kabale University
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publisher Столичная издательская компания
record_format Article
series Рациональная фармакотерапия в кардиологии
spelling doaj-art-eb97971947834136bc13fedc21444caa2025-08-23T10:00:31ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532019-05-0115227127610.20996/1819-6446-2019-15-2-271-2761605How to solve the problem of drug choice within the same class from the standpoint of evidence-based medicine?S. Yu. Martsevich0National Medical Research Center for Preventive MedicineThe question of the possibility of the most effective drug choosing within one class from the standpoint of evidence-based medicine is considered in the article. Drugs belonging to the same class may have both great similarities and significant differences. This is demonstrated by the example of different classes of drugs (beta-blockers, angiotensin-converting enzyme inhibitors, and new oral anticoagulants). The choice of the most effective (from the standpoint of evidence-based medicine) is impossible if there are no direct comparisons in randomized controlled studies between drugs of the same class that have demonstrated their effectiveness separately. Analysis of observational studies (large databases, registers) to identify the most effective drug in a class cannot be used to solve the problem of the superiority of a drug within a class.https://www.rpcardio.online/jour/article/view/1925class effectrandomized controlled studiesproblems of drug choice within the same class
spellingShingle S. Yu. Martsevich
How to solve the problem of drug choice within the same class from the standpoint of evidence-based medicine?
Рациональная фармакотерапия в кардиологии
class effect
randomized controlled studies
problems of drug choice within the same class
title How to solve the problem of drug choice within the same class from the standpoint of evidence-based medicine?
title_full How to solve the problem of drug choice within the same class from the standpoint of evidence-based medicine?
title_fullStr How to solve the problem of drug choice within the same class from the standpoint of evidence-based medicine?
title_full_unstemmed How to solve the problem of drug choice within the same class from the standpoint of evidence-based medicine?
title_short How to solve the problem of drug choice within the same class from the standpoint of evidence-based medicine?
title_sort how to solve the problem of drug choice within the same class from the standpoint of evidence based medicine
topic class effect
randomized controlled studies
problems of drug choice within the same class
url https://www.rpcardio.online/jour/article/view/1925
work_keys_str_mv AT syumartsevich howtosolvetheproblemofdrugchoicewithinthesameclassfromthestandpointofevidencebasedmedicine