Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the interaction between two algorithms

Objectives During a ‘cannot intubate, cannot oxygenate’ situation, asphyxia can lead to cardiac arrest. In this stressful situation, two complex algorithms facilitate decision-making to save a patient’s life: difficult airway management and cardiopulmonary resuscitation. However, the extent to which...

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Main Authors: Thomas Ott, Jascha Stracke, Susanna Sellin, Marc Kriege, Gerrit Toenges, Carsten Lott, Sebastian Kuhn, Kristin Engelhard
Format: Article
Language:English
Published: BMJ Publishing Group 2019-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/11/e030430.full
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author Thomas Ott
Jascha Stracke
Susanna Sellin
Marc Kriege
Gerrit Toenges
Carsten Lott
Sebastian Kuhn
Kristin Engelhard
author_facet Thomas Ott
Jascha Stracke
Susanna Sellin
Marc Kriege
Gerrit Toenges
Carsten Lott
Sebastian Kuhn
Kristin Engelhard
author_sort Thomas Ott
collection DOAJ
description Objectives During a ‘cannot intubate, cannot oxygenate’ situation, asphyxia can lead to cardiac arrest. In this stressful situation, two complex algorithms facilitate decision-making to save a patient’s life: difficult airway management and cardiopulmonary resuscitation. However, the extent to which competition between the two algorithms causes conflicts in the execution of pivotal treatment remains unknown. Due to the rare incidence of this situation and the very low feasibility of such an evaluation in clinical reality, we decided to perform a randomised crossover simulation research study. We propose that even experienced healthcare providers delay cricothyrotomy, a lifesaving approach, due to concurrent cardiopulmonary resuscitation in a ‘cannot intubate, cannot oxygenate’ situation.Design Due to the rare incidence and dynamics of such a situation, we conducted a randomised crossover simulation research study.Setting We collected data in our institutional simulation centre between November 2016 and November 2017.Participants We included 40 experienced staff anaesthesiologists at our tertiary university hospital centre.Intervention The participants treated two simulated patients, both requiring cricothyrotomy: one patient required cardiopulmonary resuscitation due to asphyxia, and one patient did not require cardiopulmonary resuscitation. Cardiopulmonary resuscitation was the intervention. Participants were evaluated by video records.Primary outcome measures The difference in ‘time to ventilation through cricothyrotomy’ between the two situations was the primary outcome measure.Results The results of 40 participants were analysed. No carry-over effects were detected in the crossover design. During cardiopulmonary resuscitation, the median time to ventilation was 22 s (IQR 3–40.5) longer than that without cardiopulmonary resuscitation (p=0.028), including the decision-making time.Conclusion Cricothyrotomy, which is the most crucial treatment for cardiac arrest in a ‘cannot intubate, cannot oxygenate’ situation, was delayed by concurrent cardiopulmonary resuscitation. If cardiopulmonary resuscitation delays cricothyrotomy, it should be interrupted to first focus on cricothyrotomy.
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spelling doaj-art-eb856880d2884ef697ee98eaa38eeda82025-08-20T02:05:13ZengBMJ Publishing GroupBMJ Open2044-60552019-11-0191110.1136/bmjopen-2019-030430Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the interaction between two algorithmsThomas Ott0Jascha Stracke1Susanna Sellin2Marc Kriege3Gerrit Toenges4Carsten Lott5Sebastian Kuhn6Kristin Engelhard71 Department of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, Germany1 Department of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, Germany1 Department of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, Germany1 Department of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, GermanyBoehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim am Rhein, Germany1 Department of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, GermanyInstitute of Digital Medicine, University Hospital Giessen-Marburg, Philipps University, Marburg, Germany1 Department of Anaesthesiology, Johannes Gutenberg Universitat Mainz, Mainz, GermanyObjectives During a ‘cannot intubate, cannot oxygenate’ situation, asphyxia can lead to cardiac arrest. In this stressful situation, two complex algorithms facilitate decision-making to save a patient’s life: difficult airway management and cardiopulmonary resuscitation. However, the extent to which competition between the two algorithms causes conflicts in the execution of pivotal treatment remains unknown. Due to the rare incidence of this situation and the very low feasibility of such an evaluation in clinical reality, we decided to perform a randomised crossover simulation research study. We propose that even experienced healthcare providers delay cricothyrotomy, a lifesaving approach, due to concurrent cardiopulmonary resuscitation in a ‘cannot intubate, cannot oxygenate’ situation.Design Due to the rare incidence and dynamics of such a situation, we conducted a randomised crossover simulation research study.Setting We collected data in our institutional simulation centre between November 2016 and November 2017.Participants We included 40 experienced staff anaesthesiologists at our tertiary university hospital centre.Intervention The participants treated two simulated patients, both requiring cricothyrotomy: one patient required cardiopulmonary resuscitation due to asphyxia, and one patient did not require cardiopulmonary resuscitation. Cardiopulmonary resuscitation was the intervention. Participants were evaluated by video records.Primary outcome measures The difference in ‘time to ventilation through cricothyrotomy’ between the two situations was the primary outcome measure.Results The results of 40 participants were analysed. No carry-over effects were detected in the crossover design. During cardiopulmonary resuscitation, the median time to ventilation was 22 s (IQR 3–40.5) longer than that without cardiopulmonary resuscitation (p=0.028), including the decision-making time.Conclusion Cricothyrotomy, which is the most crucial treatment for cardiac arrest in a ‘cannot intubate, cannot oxygenate’ situation, was delayed by concurrent cardiopulmonary resuscitation. If cardiopulmonary resuscitation delays cricothyrotomy, it should be interrupted to first focus on cricothyrotomy.https://bmjopen.bmj.com/content/9/11/e030430.full
spellingShingle Thomas Ott
Jascha Stracke
Susanna Sellin
Marc Kriege
Gerrit Toenges
Carsten Lott
Sebastian Kuhn
Kristin Engelhard
Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the interaction between two algorithms
BMJ Open
title Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the interaction between two algorithms
title_full Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the interaction between two algorithms
title_fullStr Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the interaction between two algorithms
title_full_unstemmed Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the interaction between two algorithms
title_short Impact of cardiopulmonary resuscitation on a cannot intubate, cannot oxygenate condition: a randomised crossover simulation research study of the interaction between two algorithms
title_sort impact of cardiopulmonary resuscitation on a cannot intubate cannot oxygenate condition a randomised crossover simulation research study of the interaction between two algorithms
url https://bmjopen.bmj.com/content/9/11/e030430.full
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