Can Clinical, Psychophysical or Psychological Variables Help in Discriminating Women with Migraines from a Tertiary Center? A Diagnostic Accuracy Study
<b>Background:</b> Migraine diagnosis is mainly clinically based on symptomatology. The objectives of this study were (1) to determine the ability of pain thresholds to differentiate between women with and without migraines and (2) to determine the ability of clinical, psychological and...
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2024-12-01
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| author | Margarita Cigarán-Mendez Juan C. Pacho-Hernández Francisco G. Fernández-Palacios Ángela Tejera-Alonso Juan A. Valera-Calero Cristina Gómez-Calero Carlos Ordás-Bandera César Fernández-de-las-Peñas |
| author_facet | Margarita Cigarán-Mendez Juan C. Pacho-Hernández Francisco G. Fernández-Palacios Ángela Tejera-Alonso Juan A. Valera-Calero Cristina Gómez-Calero Carlos Ordás-Bandera César Fernández-de-las-Peñas |
| author_sort | Margarita Cigarán-Mendez |
| collection | DOAJ |
| description | <b>Background:</b> Migraine diagnosis is mainly clinically based on symptomatology. The objectives of this study were (1) to determine the ability of pain thresholds to differentiate between women with and without migraines and (2) to determine the ability of clinical, psychological and psychophysical variables to differentiate between women with episodic and chronic migraines. A diagnostic accuracy study was conducted. <b>Methods:</b> Pressure-pain thresholds (PPTs) at one trigeminal (temporalis muscle) and one extra-trigeminal (cervical spine) and two distant-pain free (second metacarpal and tibialis anterior muscle) areas, as well as dynamic pain thresholds (DPTs), were bilaterally assessed in 100 women with migraines, recruited from tertiary hospitals (50% episodic, 50% chronic), and 50 comparable women without headaches. Migraine pain features (headache diary), migraine-associated burden (HDI), anxiety and depressive levels (HADS) and state (STAI-S)–trait (STAI-T) anxiety were also evaluated. The area under the receiver operating characteristic (ROC) curve, with optimal cut-off points, as well as the sensitivity, specificity and positive/negative likelihood ratios (LR) for each variable, were calculated. The women with migraines showed lower PPTs and DPTs than those without migraines. <b>Results:</b> The women with chronic migraines showed lower PPTs in the temporalis muscle than the women with episodic migraines. No clinical, psychological or psychophysical variables exhibited acceptable ROC values (≥0.7) for differentiating between women with and without migraines or between women with episodic and chronic migraines. <b>Conclusions:</b> Although the women with migraines had widespread pressure-pain hyperalgesia, neither the clinical, psychological nor psychophysical (pain threshold) variable exhibited the proper diagnostic accuracy to distinguish between women with and without migraines or between women with episodic and chronic migraines. New studies should clarify the clinical relevance of the findings of the current study. |
| format | Article |
| id | doaj-art-eb81fbbf041c42e99a714d1352805b92 |
| institution | DOAJ |
| issn | 2075-4418 |
| language | English |
| publishDate | 2024-12-01 |
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| spelling | doaj-art-eb81fbbf041c42e99a714d1352805b922025-08-20T02:53:19ZengMDPI AGDiagnostics2075-44182024-12-011424280510.3390/diagnostics14242805Can Clinical, Psychophysical or Psychological Variables Help in Discriminating Women with Migraines from a Tertiary Center? A Diagnostic Accuracy StudyMargarita Cigarán-Mendez0Juan C. Pacho-Hernández1Francisco G. Fernández-Palacios2Ángela Tejera-Alonso3Juan A. Valera-Calero4Cristina Gómez-Calero5Carlos Ordás-Bandera6César Fernández-de-las-Peñas7Department of Psychology, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainDepartment of Psychology, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainDepartment of Psychology, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainDepartment of Psychology, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainDepartment of Radiology, Rehabilitation and Physiotherapy, Faculty of Nursery, Physiotherapy and Podiatry, Complutense University of Madrid, 28040 Madrid, SpainDepartment Physical Therapy, Occupational Therapy, Rehabilitation, and Physical Medicine, Universidad Rey Juan Carlos, 28922 Alcorcón, SpainDepartment of Neurology, Hospital Rey Juan Carlos, 28933 Móstoles, SpainDepartment Physical Therapy, Occupational Therapy, Rehabilitation, and Physical Medicine, Universidad Rey Juan Carlos, 28922 Alcorcón, Spain<b>Background:</b> Migraine diagnosis is mainly clinically based on symptomatology. The objectives of this study were (1) to determine the ability of pain thresholds to differentiate between women with and without migraines and (2) to determine the ability of clinical, psychological and psychophysical variables to differentiate between women with episodic and chronic migraines. A diagnostic accuracy study was conducted. <b>Methods:</b> Pressure-pain thresholds (PPTs) at one trigeminal (temporalis muscle) and one extra-trigeminal (cervical spine) and two distant-pain free (second metacarpal and tibialis anterior muscle) areas, as well as dynamic pain thresholds (DPTs), were bilaterally assessed in 100 women with migraines, recruited from tertiary hospitals (50% episodic, 50% chronic), and 50 comparable women without headaches. Migraine pain features (headache diary), migraine-associated burden (HDI), anxiety and depressive levels (HADS) and state (STAI-S)–trait (STAI-T) anxiety were also evaluated. The area under the receiver operating characteristic (ROC) curve, with optimal cut-off points, as well as the sensitivity, specificity and positive/negative likelihood ratios (LR) for each variable, were calculated. The women with migraines showed lower PPTs and DPTs than those without migraines. <b>Results:</b> The women with chronic migraines showed lower PPTs in the temporalis muscle than the women with episodic migraines. No clinical, psychological or psychophysical variables exhibited acceptable ROC values (≥0.7) for differentiating between women with and without migraines or between women with episodic and chronic migraines. <b>Conclusions:</b> Although the women with migraines had widespread pressure-pain hyperalgesia, neither the clinical, psychological nor psychophysical (pain threshold) variable exhibited the proper diagnostic accuracy to distinguish between women with and without migraines or between women with episodic and chronic migraines. New studies should clarify the clinical relevance of the findings of the current study.https://www.mdpi.com/2075-4418/14/24/2805migrainediagnostic accuracypressure painburdenanxietydepression |
| spellingShingle | Margarita Cigarán-Mendez Juan C. Pacho-Hernández Francisco G. Fernández-Palacios Ángela Tejera-Alonso Juan A. Valera-Calero Cristina Gómez-Calero Carlos Ordás-Bandera César Fernández-de-las-Peñas Can Clinical, Psychophysical or Psychological Variables Help in Discriminating Women with Migraines from a Tertiary Center? A Diagnostic Accuracy Study Diagnostics migraine diagnostic accuracy pressure pain burden anxiety depression |
| title | Can Clinical, Psychophysical or Psychological Variables Help in Discriminating Women with Migraines from a Tertiary Center? A Diagnostic Accuracy Study |
| title_full | Can Clinical, Psychophysical or Psychological Variables Help in Discriminating Women with Migraines from a Tertiary Center? A Diagnostic Accuracy Study |
| title_fullStr | Can Clinical, Psychophysical or Psychological Variables Help in Discriminating Women with Migraines from a Tertiary Center? A Diagnostic Accuracy Study |
| title_full_unstemmed | Can Clinical, Psychophysical or Psychological Variables Help in Discriminating Women with Migraines from a Tertiary Center? A Diagnostic Accuracy Study |
| title_short | Can Clinical, Psychophysical or Psychological Variables Help in Discriminating Women with Migraines from a Tertiary Center? A Diagnostic Accuracy Study |
| title_sort | can clinical psychophysical or psychological variables help in discriminating women with migraines from a tertiary center a diagnostic accuracy study |
| topic | migraine diagnostic accuracy pressure pain burden anxiety depression |
| url | https://www.mdpi.com/2075-4418/14/24/2805 |
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