Efficacy of different dosages of common uric acid-lowering medications in gout patients: a network meta-analysis of randomized control trials

Efficacy of different dosages of common uric acid-lowering medications in gout patients: a network meta-analysis of randomized control trials

PurposeUrate lowering therapy (ULT) is extensively utilized for managing patients with gout. This study aims to compare the efficacy of different ULTs on serum uric acid (SUC) levels, gout flares, and adverse events (AEs) in gout patients.MethodsStudies comparing the efficacy of febuxostat, allopuri...

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Bibliographic Details
Main Authors: Xiaojia Zheng, Cunxiang Xie, Jinying Fang, Zhenghui Huang, Jian Huang, Luming Zhao, Guancheng Ye, Hailong Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
gout
common uric acid-lowering medications
dosage
network meta-analysis
dose-response
RCTs
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1565530/full
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