Influence of proteinoids on calcium carbonate polymorphs precipitation in supersaturated solutions

Proteinoids, or thermal proteins, are amino acid polymers formed at high temperatures by non-biological processes. Pro- teinoids form microspheres in liquids. The microspheres exhibit electrical activity similar to that of neurons. The electrically spiking microspheres are seen as proto-neurons capa...

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Main Authors: Panagiotis Mougkogiannis, Andrew Adamatzky
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Results in Chemistry
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211715624006465
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author Panagiotis Mougkogiannis
Andrew Adamatzky
author_facet Panagiotis Mougkogiannis
Andrew Adamatzky
author_sort Panagiotis Mougkogiannis
collection DOAJ
description Proteinoids, or thermal proteins, are amino acid polymers formed at high temperatures by non-biological processes. Pro- teinoids form microspheres in liquids. The microspheres exhibit electrical activity similar to that of neurons. The electrically spiking microspheres are seen as proto-neurons capable of forming networks and carrying out information transmission and processing. Previously, we demonstrated that ensembles of proteinoid microspheres can respond to optical and electrical stimulation, implement logical gates, recognise arbitrary wave forms, and undergo learning. Thus, the ensembles of proteinoid microspheres can be seen as proto-brains. In present paper we decided to uncover morphologies of these proto-brains. We utilise a supersaturated solution of calcium carbonate to facilitate the crystallisation of proteinoids and subsequently generate proteinoid brain structures. Our hypothesis suggests that calcium carbonate crystals have the potential to serve as scaffolds and connectors for proteinoid microspheres, thereby improving their electrical properties and facilitating communication. In this section, we outline the experimental methods and techniques used in our study. We share our findings and results regarding the morphology, composition, stability, and functionality of proteinoid brain structures. We discuss the implications and applications of our work in the fields of bio-inspired computing, artificial neural networks, and origin of life research.
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spelling doaj-art-eb78c186b762448f896fc6647d18eba82025-01-29T05:00:40ZengElsevierResults in Chemistry2211-71562025-01-0113101950Influence of proteinoids on calcium carbonate polymorphs precipitation in supersaturated solutionsPanagiotis Mougkogiannis0Andrew Adamatzky1Corresponding author.; Unconventional Computing Laboratory, UWE, Bristol, UKUnconventional Computing Laboratory, UWE, Bristol, UKProteinoids, or thermal proteins, are amino acid polymers formed at high temperatures by non-biological processes. Pro- teinoids form microspheres in liquids. The microspheres exhibit electrical activity similar to that of neurons. The electrically spiking microspheres are seen as proto-neurons capable of forming networks and carrying out information transmission and processing. Previously, we demonstrated that ensembles of proteinoid microspheres can respond to optical and electrical stimulation, implement logical gates, recognise arbitrary wave forms, and undergo learning. Thus, the ensembles of proteinoid microspheres can be seen as proto-brains. In present paper we decided to uncover morphologies of these proto-brains. We utilise a supersaturated solution of calcium carbonate to facilitate the crystallisation of proteinoids and subsequently generate proteinoid brain structures. Our hypothesis suggests that calcium carbonate crystals have the potential to serve as scaffolds and connectors for proteinoid microspheres, thereby improving their electrical properties and facilitating communication. In this section, we outline the experimental methods and techniques used in our study. We share our findings and results regarding the morphology, composition, stability, and functionality of proteinoid brain structures. We discuss the implications and applications of our work in the fields of bio-inspired computing, artificial neural networks, and origin of life research.http://www.sciencedirect.com/science/article/pii/S2211715624006465Thermal proteinsProteinoidsMicrospheresUnconventional computingCalcium carbonate
spellingShingle Panagiotis Mougkogiannis
Andrew Adamatzky
Influence of proteinoids on calcium carbonate polymorphs precipitation in supersaturated solutions
Results in Chemistry
Thermal proteins
Proteinoids
Microspheres
Unconventional computing
Calcium carbonate
title Influence of proteinoids on calcium carbonate polymorphs precipitation in supersaturated solutions
title_full Influence of proteinoids on calcium carbonate polymorphs precipitation in supersaturated solutions
title_fullStr Influence of proteinoids on calcium carbonate polymorphs precipitation in supersaturated solutions
title_full_unstemmed Influence of proteinoids on calcium carbonate polymorphs precipitation in supersaturated solutions
title_short Influence of proteinoids on calcium carbonate polymorphs precipitation in supersaturated solutions
title_sort influence of proteinoids on calcium carbonate polymorphs precipitation in supersaturated solutions
topic Thermal proteins
Proteinoids
Microspheres
Unconventional computing
Calcium carbonate
url http://www.sciencedirect.com/science/article/pii/S2211715624006465
work_keys_str_mv AT panagiotismougkogiannis influenceofproteinoidsoncalciumcarbonatepolymorphsprecipitationinsupersaturatedsolutions
AT andrewadamatzky influenceofproteinoidsoncalciumcarbonatepolymorphsprecipitationinsupersaturatedsolutions