Single-Lung Transplantation in the Setting of Aborted Bilateral Lung Transplantation
Background. The outcome of patients undergoing a single-lung transplant in the setting of an aborted bilateral lung transplant is unclear. Methods. A retrospective review of single lung transplants at an institutional program. Results. Of the 543 lung transplants performed over the last 10 years, 31...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2011/535649 |
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| author | Varun Puri Tracey Guthrie Masina Scavuzzo Daniel Kreisel Alexander S. Krupnick G. Alexander Patterson Bryan F. Meyers |
| author_facet | Varun Puri Tracey Guthrie Masina Scavuzzo Daniel Kreisel Alexander S. Krupnick G. Alexander Patterson Bryan F. Meyers |
| author_sort | Varun Puri |
| collection | DOAJ |
| description | Background. The outcome of patients undergoing a single-lung transplant in the setting of an aborted bilateral lung transplant is unclear. Methods. A retrospective review of single lung transplants at an institutional program. Results. Of the 543 lung transplants performed over the last 10 years, 31 (5.7%) were single-lung transplants. Nineteen of 31 (61%) were planned single-lung transplants, while 12/31 (39%)
were intraoperatively aborted, double lung transplants converted to single-lung transplants. The aborted and planned groups were
similar in age, lung allocation score and NYHA status. The reasons for aborted double lung transplantation were cardiac/hemodynamic instability 4/12 (33%), difficult pneumonectomy 3/12 (25%), size mismatch 4/12(33%), and technical issues 1/12 (8%). The aborted group had higher CPB utilization (5/12 versus 1/19, 𝑃=.02), similar ischemic times (260 versus 234 min) and similar incidence of grade 3 primary graft dysfunction (6/12 versus 3/19, 𝑃=.13). ECMO was required for graft dysfunction in 2 patients in the aborted group. The one and two-year survival was 84% and 79% in the planned group and 62% and 52% in the aborted group, respectively. Conclusions. Patients undergoing single-lung transplantation in the setting of an aborted bilateral lung transplant may be at a higher risk of
worse outcomes. |
| format | Article |
| id | doaj-art-eb773c9190184868b10e2eab89930d69 |
| institution | DOAJ |
| issn | 2090-0007 2090-0015 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Transplantation |
| spelling | doaj-art-eb773c9190184868b10e2eab89930d692025-08-20T03:21:18ZengWileyJournal of Transplantation2090-00072090-00152011-01-01201110.1155/2011/535649535649Single-Lung Transplantation in the Setting of Aborted Bilateral Lung TransplantationVarun Puri0Tracey Guthrie1Masina Scavuzzo2Daniel Kreisel3Alexander S. Krupnick4G. Alexander Patterson5Bryan F. Meyers6Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USADepartment of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USADepartment of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USADepartment of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USADepartment of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USADepartment of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USADepartment of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USABackground. The outcome of patients undergoing a single-lung transplant in the setting of an aborted bilateral lung transplant is unclear. Methods. A retrospective review of single lung transplants at an institutional program. Results. Of the 543 lung transplants performed over the last 10 years, 31 (5.7%) were single-lung transplants. Nineteen of 31 (61%) were planned single-lung transplants, while 12/31 (39%) were intraoperatively aborted, double lung transplants converted to single-lung transplants. The aborted and planned groups were similar in age, lung allocation score and NYHA status. The reasons for aborted double lung transplantation were cardiac/hemodynamic instability 4/12 (33%), difficult pneumonectomy 3/12 (25%), size mismatch 4/12(33%), and technical issues 1/12 (8%). The aborted group had higher CPB utilization (5/12 versus 1/19, 𝑃=.02), similar ischemic times (260 versus 234 min) and similar incidence of grade 3 primary graft dysfunction (6/12 versus 3/19, 𝑃=.13). ECMO was required for graft dysfunction in 2 patients in the aborted group. The one and two-year survival was 84% and 79% in the planned group and 62% and 52% in the aborted group, respectively. Conclusions. Patients undergoing single-lung transplantation in the setting of an aborted bilateral lung transplant may be at a higher risk of worse outcomes.http://dx.doi.org/10.1155/2011/535649 |
| spellingShingle | Varun Puri Tracey Guthrie Masina Scavuzzo Daniel Kreisel Alexander S. Krupnick G. Alexander Patterson Bryan F. Meyers Single-Lung Transplantation in the Setting of Aborted Bilateral Lung Transplantation Journal of Transplantation |
| title | Single-Lung Transplantation in the Setting of Aborted Bilateral Lung Transplantation |
| title_full | Single-Lung Transplantation in the Setting of Aborted Bilateral Lung Transplantation |
| title_fullStr | Single-Lung Transplantation in the Setting of Aborted Bilateral Lung Transplantation |
| title_full_unstemmed | Single-Lung Transplantation in the Setting of Aborted Bilateral Lung Transplantation |
| title_short | Single-Lung Transplantation in the Setting of Aborted Bilateral Lung Transplantation |
| title_sort | single lung transplantation in the setting of aborted bilateral lung transplantation |
| url | http://dx.doi.org/10.1155/2011/535649 |
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