Retinopathy and vision-related quality of life in blood dyscrasias

Purpose: To study the association of retinopathy with vision-related quality of life in patients with blood dyscrasias. Settings and Design: A cross-sectional observational study was conducted at a university-based hospital. Methods: Two hundred patients with blood dyscrasias underwent comprehensive...

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Main Authors: Lipa Mohanty, Appurv Kachhwaha, Alokit Sharma
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.4103/IJO.IJO_564_24
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author Lipa Mohanty
Appurv Kachhwaha
Alokit Sharma
author_facet Lipa Mohanty
Appurv Kachhwaha
Alokit Sharma
author_sort Lipa Mohanty
collection DOAJ
description Purpose: To study the association of retinopathy with vision-related quality of life in patients with blood dyscrasias. Settings and Design: A cross-sectional observational study was conducted at a university-based hospital. Methods: Two hundred patients with blood dyscrasias underwent comprehensive ocular examination, including dilated fundus examination. Vision-related quality of life was assessed using the National Eye Institute Visual Functioning Questionnaire-25 (NEI-VFQ-25). Results: Retinopathy was observed in 99 out of 200 patients (49.50%) with blood dyscrasias. The most common retinal findings were venous tortuosity with dilation (31.70%), intraretinal hemorrhages (27.88%), soft exudates (12.50%), white-centered hemorrhages (12.50%), and arteriolar attenuation (12.50%). A significant association was found between retinopathy in blood dyscrasias and NEI-VFQ subscales of general vision (P value: 0.01**), near activities (P value: 0.04*), distance activities (P value: 0.01**), mental health (P value: 0.01**), color vision (P value: 0.01**), peripheral vision (P value: 0.01**), role difficulties (P value: 0.01**), and social functioning (P value: 0.01**). Conclusion: The study highlights the prevalence of retinopathy in blood dyscrasia patients and its detrimental impact on vision-related quality of life. Regular fundus examinations are imperative for early detection and management of retinopathy to prevent significant visual impairment. Further research is warranted to elucidate underlying mechanisms and improve clinical management strategies.
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spelling doaj-art-eb771b628a16405f94dcbdd58a6fc1ae2025-08-20T01:48:25ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892025-01-0173Suppl 1S107S11110.4103/IJO.IJO_564_24Retinopathy and vision-related quality of life in blood dyscrasiasLipa MohantyAppurv KachhwahaAlokit SharmaPurpose: To study the association of retinopathy with vision-related quality of life in patients with blood dyscrasias. Settings and Design: A cross-sectional observational study was conducted at a university-based hospital. Methods: Two hundred patients with blood dyscrasias underwent comprehensive ocular examination, including dilated fundus examination. Vision-related quality of life was assessed using the National Eye Institute Visual Functioning Questionnaire-25 (NEI-VFQ-25). Results: Retinopathy was observed in 99 out of 200 patients (49.50%) with blood dyscrasias. The most common retinal findings were venous tortuosity with dilation (31.70%), intraretinal hemorrhages (27.88%), soft exudates (12.50%), white-centered hemorrhages (12.50%), and arteriolar attenuation (12.50%). A significant association was found between retinopathy in blood dyscrasias and NEI-VFQ subscales of general vision (P value: 0.01**), near activities (P value: 0.04*), distance activities (P value: 0.01**), mental health (P value: 0.01**), color vision (P value: 0.01**), peripheral vision (P value: 0.01**), role difficulties (P value: 0.01**), and social functioning (P value: 0.01**). Conclusion: The study highlights the prevalence of retinopathy in blood dyscrasia patients and its detrimental impact on vision-related quality of life. Regular fundus examinations are imperative for early detection and management of retinopathy to prevent significant visual impairment. Further research is warranted to elucidate underlying mechanisms and improve clinical management strategies.https://journals.lww.com/10.4103/IJO.IJO_564_24blood dyscrasiasretinopathyvision-related quality of lifevisual impairment
spellingShingle Lipa Mohanty
Appurv Kachhwaha
Alokit Sharma
Retinopathy and vision-related quality of life in blood dyscrasias
Indian Journal of Ophthalmology
blood dyscrasias
retinopathy
vision-related quality of life
visual impairment
title Retinopathy and vision-related quality of life in blood dyscrasias
title_full Retinopathy and vision-related quality of life in blood dyscrasias
title_fullStr Retinopathy and vision-related quality of life in blood dyscrasias
title_full_unstemmed Retinopathy and vision-related quality of life in blood dyscrasias
title_short Retinopathy and vision-related quality of life in blood dyscrasias
title_sort retinopathy and vision related quality of life in blood dyscrasias
topic blood dyscrasias
retinopathy
vision-related quality of life
visual impairment
url https://journals.lww.com/10.4103/IJO.IJO_564_24
work_keys_str_mv AT lipamohanty retinopathyandvisionrelatedqualityoflifeinblooddyscrasias
AT appurvkachhwaha retinopathyandvisionrelatedqualityoflifeinblooddyscrasias
AT alokitsharma retinopathyandvisionrelatedqualityoflifeinblooddyscrasias