Risk-Based Screening for Thyroid Dysfunction during Pregnancy
Objective. We conducted the study to see the incidence of thyroid dysfunction in women with obstetrical high-risk factors. Methods. We retrospectively reviewed medical charts of high-risk pregnant women who had examination for thyroid function during pregnancy. Women were divided according to clinic...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Pregnancy |
| Online Access: | http://dx.doi.org/10.1155/2013/619718 |
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| author | Masanao Ohashi Seishi Furukawa Kaori Michikata Katsuhide Kai Hiroshi Sameshima Tsuyomu Ikenoue |
| author_facet | Masanao Ohashi Seishi Furukawa Kaori Michikata Katsuhide Kai Hiroshi Sameshima Tsuyomu Ikenoue |
| author_sort | Masanao Ohashi |
| collection | DOAJ |
| description | Objective. We conducted the study to see the incidence of thyroid dysfunction in women with obstetrical high-risk factors. Methods. We retrospectively reviewed medical charts of high-risk pregnant women who had examination for thyroid function during pregnancy. Women were divided according to clinical presentation, symptoms of thyroid disease and those with a personal history of thyroid disease (thyroid disease, n=32), intrauterine growth restriction (IUGR, n=115), diabetes mellitus (diabetes, n=115), hypertension (n=63), intrauterine fetal death (IUFD, n=52), and placental abruption (abruption, n=15). The incidence of thyroid dysfunctions including hyperthyroidism or hypothyroidism was compared. Results. The overall prevalence of thyroid dysfunction was 24.7%. The incidence of thyroid dysfunction in each group was as follows: 31% in thyroid disease, 25% in IUGR, 30% in diabetes, 27% in hypertension, 12% in IUFD, and 7% in abruption. Except IUFD, the incidence was not statistically significant from the group of thyroid disease (thyroid disease versus IUFD, P=0.03 by χ2 test). Thyroid disease represented for only 10% of all thyroid dysfunctions. Conclusion. Testing of women with a personal history or current symptoms of thyroid disease during pregnancy may be insufficient to detect women with thyroid dysfunction, who will become at high-risk pregnancy. |
| format | Article |
| id | doaj-art-eb76666228af404f89f2b302f2782702 |
| institution | Kabale University |
| issn | 2090-2727 2090-2735 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Pregnancy |
| spelling | doaj-art-eb76666228af404f89f2b302f27827022025-02-03T05:58:43ZengWileyJournal of Pregnancy2090-27272090-27352013-01-01201310.1155/2013/619718619718Risk-Based Screening for Thyroid Dysfunction during PregnancyMasanao Ohashi0Seishi Furukawa1Kaori Michikata2Katsuhide Kai3Hiroshi Sameshima4Tsuyomu Ikenoue5Department of Obstetrics & Gynecology, Miyazaki Medical Association Hospital, 738-1 Shinbepputyo-Funato, Miyazaki 880-0834, JapanDepartment of Obstetrics & Gynecology, Faculty of Medicine, University of Miyazaki, 5200 Kihara-Kiyotake, Miyazaki 889-1692, JapanDepartment of Obstetrics & Gynecology, Miyazaki Medical Association Hospital, 738-1 Shinbepputyo-Funato, Miyazaki 880-0834, JapanDepartment of Obstetrics & Gynecology, Miyazaki Medical Association Hospital, 738-1 Shinbepputyo-Funato, Miyazaki 880-0834, JapanDepartment of Obstetrics & Gynecology, Faculty of Medicine, University of Miyazaki, 5200 Kihara-Kiyotake, Miyazaki 889-1692, JapanDepartment of Obstetrics & Gynecology, Faculty of Medicine, University of Miyazaki, 5200 Kihara-Kiyotake, Miyazaki 889-1692, JapanObjective. We conducted the study to see the incidence of thyroid dysfunction in women with obstetrical high-risk factors. Methods. We retrospectively reviewed medical charts of high-risk pregnant women who had examination for thyroid function during pregnancy. Women were divided according to clinical presentation, symptoms of thyroid disease and those with a personal history of thyroid disease (thyroid disease, n=32), intrauterine growth restriction (IUGR, n=115), diabetes mellitus (diabetes, n=115), hypertension (n=63), intrauterine fetal death (IUFD, n=52), and placental abruption (abruption, n=15). The incidence of thyroid dysfunctions including hyperthyroidism or hypothyroidism was compared. Results. The overall prevalence of thyroid dysfunction was 24.7%. The incidence of thyroid dysfunction in each group was as follows: 31% in thyroid disease, 25% in IUGR, 30% in diabetes, 27% in hypertension, 12% in IUFD, and 7% in abruption. Except IUFD, the incidence was not statistically significant from the group of thyroid disease (thyroid disease versus IUFD, P=0.03 by χ2 test). Thyroid disease represented for only 10% of all thyroid dysfunctions. Conclusion. Testing of women with a personal history or current symptoms of thyroid disease during pregnancy may be insufficient to detect women with thyroid dysfunction, who will become at high-risk pregnancy.http://dx.doi.org/10.1155/2013/619718 |
| spellingShingle | Masanao Ohashi Seishi Furukawa Kaori Michikata Katsuhide Kai Hiroshi Sameshima Tsuyomu Ikenoue Risk-Based Screening for Thyroid Dysfunction during Pregnancy Journal of Pregnancy |
| title | Risk-Based Screening for Thyroid Dysfunction during Pregnancy |
| title_full | Risk-Based Screening for Thyroid Dysfunction during Pregnancy |
| title_fullStr | Risk-Based Screening for Thyroid Dysfunction during Pregnancy |
| title_full_unstemmed | Risk-Based Screening for Thyroid Dysfunction during Pregnancy |
| title_short | Risk-Based Screening for Thyroid Dysfunction during Pregnancy |
| title_sort | risk based screening for thyroid dysfunction during pregnancy |
| url | http://dx.doi.org/10.1155/2013/619718 |
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