Nano-Biofungicides and Bio-Nanofungicides: State of the Art of Innovative Tools for Controlling Resistant Phytopathogens
Fungal diseases represent a significant threat to global agriculture, leading to substantial crop losses and endangering food security worldwide. Conventional chemical fungicides, while effective, are increasingly criticized for their detrimental environmental impacts, including soil degradation, wa...
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MDPI AG
2025-04-01
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| Series: | Biophysica |
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| Online Access: | https://www.mdpi.com/2673-4125/5/2/15 |
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| author | José Sebastian Dávila Costa Cintia Mariana Romero |
| author_facet | José Sebastian Dávila Costa Cintia Mariana Romero |
| author_sort | José Sebastian Dávila Costa |
| collection | DOAJ |
| description | Fungal diseases represent a significant threat to global agriculture, leading to substantial crop losses and endangering food security worldwide. Conventional chemical fungicides, while effective, are increasingly criticized for their detrimental environmental impacts, including soil degradation, water contamination, and the disruption of non-target organisms. Additionally, the overuse of these fungicides has accelerated the emergence of resistant fungal strains, further challenging disease management strategies. In response to these issues, bio-nanofungicides and nano-biofungicides have emerged as a cutting-edge solution, combining biocompatibility, environmental safety, and enhanced efficacy. These advanced formulations integrate bio-based agents, such as microbial metabolites or plant extracts, with nanotechnology to improve their stability, controlled release, and targeted delivery. Chitosan, silica, and silver nanoparticles were extensively studied for their ability to encapsulate bioactive compounds or because of their outstanding antifungal activity, while minimizing environmental residues. Recent studies demonstrated the potential of nano-based fungicides to address critical gaps in sustainable agriculture, with promising applications in integrated pest management systems. Here, we summarize the last advances in the development of bio-nanofungicides and nano-biofungicides and analyze the main differences between them. In addition, challenges such as large-scale production, regulatory approval, and comprehensive risk assessments are discussed. |
| format | Article |
| id | doaj-art-eb6d074d23bd49d282eabc004f8180bd |
| institution | OA Journals |
| issn | 2673-4125 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
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| series | Biophysica |
| spelling | doaj-art-eb6d074d23bd49d282eabc004f8180bd2025-08-20T02:24:37ZengMDPI AGBiophysica2673-41252025-04-01521510.3390/biophysica5020015Nano-Biofungicides and Bio-Nanofungicides: State of the Art of Innovative Tools for Controlling Resistant PhytopathogensJosé Sebastian Dávila Costa0Cintia Mariana Romero1Planta Piloto de Procesos Industriales Microbiológicos—(PROIMI-CONICET), Av. Belgrano y Pasaje Caseros, Tucumán T4001 MVB, ArgentinaPlanta Piloto de Procesos Industriales Microbiológicos—(PROIMI-CONICET), Av. Belgrano y Pasaje Caseros, Tucumán T4001 MVB, ArgentinaFungal diseases represent a significant threat to global agriculture, leading to substantial crop losses and endangering food security worldwide. Conventional chemical fungicides, while effective, are increasingly criticized for their detrimental environmental impacts, including soil degradation, water contamination, and the disruption of non-target organisms. Additionally, the overuse of these fungicides has accelerated the emergence of resistant fungal strains, further challenging disease management strategies. In response to these issues, bio-nanofungicides and nano-biofungicides have emerged as a cutting-edge solution, combining biocompatibility, environmental safety, and enhanced efficacy. These advanced formulations integrate bio-based agents, such as microbial metabolites or plant extracts, with nanotechnology to improve their stability, controlled release, and targeted delivery. Chitosan, silica, and silver nanoparticles were extensively studied for their ability to encapsulate bioactive compounds or because of their outstanding antifungal activity, while minimizing environmental residues. Recent studies demonstrated the potential of nano-based fungicides to address critical gaps in sustainable agriculture, with promising applications in integrated pest management systems. Here, we summarize the last advances in the development of bio-nanofungicides and nano-biofungicides and analyze the main differences between them. In addition, challenges such as large-scale production, regulatory approval, and comprehensive risk assessments are discussed.https://www.mdpi.com/2673-4125/5/2/15bio-nanofungicidenano-biofungicidessustainable agriculturenanotechnology-based antifungalsintegrated pest management |
| spellingShingle | José Sebastian Dávila Costa Cintia Mariana Romero Nano-Biofungicides and Bio-Nanofungicides: State of the Art of Innovative Tools for Controlling Resistant Phytopathogens Biophysica bio-nanofungicide nano-biofungicides sustainable agriculture nanotechnology-based antifungals integrated pest management |
| title | Nano-Biofungicides and Bio-Nanofungicides: State of the Art of Innovative Tools for Controlling Resistant Phytopathogens |
| title_full | Nano-Biofungicides and Bio-Nanofungicides: State of the Art of Innovative Tools for Controlling Resistant Phytopathogens |
| title_fullStr | Nano-Biofungicides and Bio-Nanofungicides: State of the Art of Innovative Tools for Controlling Resistant Phytopathogens |
| title_full_unstemmed | Nano-Biofungicides and Bio-Nanofungicides: State of the Art of Innovative Tools for Controlling Resistant Phytopathogens |
| title_short | Nano-Biofungicides and Bio-Nanofungicides: State of the Art of Innovative Tools for Controlling Resistant Phytopathogens |
| title_sort | nano biofungicides and bio nanofungicides state of the art of innovative tools for controlling resistant phytopathogens |
| topic | bio-nanofungicide nano-biofungicides sustainable agriculture nanotechnology-based antifungals integrated pest management |
| url | https://www.mdpi.com/2673-4125/5/2/15 |
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