Connexin hemichannels and early atrophic signaling in muscle during sepsis

Sepsis pathogenesis is complex, and effective treatments are limited, leading to high mortality rates between 20% and 55%. Early identification of factors contributing to sepsis-related muscle dysfunction is critical for risk stratification and potential therapeutic development. The immune response...

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Main Authors: Elisa Balboa, Fujiko Saavedra, Luis A. Cea, Aníbal A. Vargas, Tomás Regueira, Juan C. Sáez
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Physiology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2025.1514769/full
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