An efficient leukemia prediction method using machine learning and deep learning with selected features.
Leukemia is a serious problem affecting both children and adults, leading to death if left untreated. Leukemia is a kind of blood cancer described by the rapid proliferation of abnormal blood cells. An early, trustworthy, and precise identification of leukemia is important to treating and saving pat...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0320669 |
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| _version_ | 1849328764134096896 |
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| author | Mahwish Ilyas Muhammad Ramzan Mohamed Deriche Khalid Mahmood Anam Naz |
| author_facet | Mahwish Ilyas Muhammad Ramzan Mohamed Deriche Khalid Mahmood Anam Naz |
| author_sort | Mahwish Ilyas |
| collection | DOAJ |
| description | Leukemia is a serious problem affecting both children and adults, leading to death if left untreated. Leukemia is a kind of blood cancer described by the rapid proliferation of abnormal blood cells. An early, trustworthy, and precise identification of leukemia is important to treating and saving patients' lives. Acute and myelogenous lymphocytic, chronic and myelogenous leukemia are the four kinds of leukemia. Manual inspection of microscopic images is frequently used to identify these malignant growth cells. Leukemia symptoms include fatigue, a lack of enthusiasm, a dull appearance, recurring illnesses, and easy blood loss. Identifying subtypes of leukemia for specialized therapy is one of the hurdles in this area. The suggested work predicts and classifies leukemia subtypes in gene data CuMiDa (GSE9476) using feature selection and ML techniques. The Curated Microarray Database (CuMiDa) collected 64 samples representing five classes of leukemia genes out of 22283 genes. The proposed approach utilizes the 25 most differentiating selected features for classification using machine and deep learning techniques. This study has a classification accuracy of 96.15% using Random Fores, 92.30 using Linear Regression, 96.15% using SVM, and 100% using LSTM. Deep learning methods have been shown to outperform traditional methods in leukemia gene classification by utilizing specific features. |
| format | Article |
| id | doaj-art-eb5f74a090cd4b28829c5539c65992fe |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-eb5f74a090cd4b28829c5539c65992fe2025-08-20T03:47:28ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01205e032066910.1371/journal.pone.0320669An efficient leukemia prediction method using machine learning and deep learning with selected features.Mahwish IlyasMuhammad RamzanMohamed DericheKhalid MahmoodAnam NazLeukemia is a serious problem affecting both children and adults, leading to death if left untreated. Leukemia is a kind of blood cancer described by the rapid proliferation of abnormal blood cells. An early, trustworthy, and precise identification of leukemia is important to treating and saving patients' lives. Acute and myelogenous lymphocytic, chronic and myelogenous leukemia are the four kinds of leukemia. Manual inspection of microscopic images is frequently used to identify these malignant growth cells. Leukemia symptoms include fatigue, a lack of enthusiasm, a dull appearance, recurring illnesses, and easy blood loss. Identifying subtypes of leukemia for specialized therapy is one of the hurdles in this area. The suggested work predicts and classifies leukemia subtypes in gene data CuMiDa (GSE9476) using feature selection and ML techniques. The Curated Microarray Database (CuMiDa) collected 64 samples representing five classes of leukemia genes out of 22283 genes. The proposed approach utilizes the 25 most differentiating selected features for classification using machine and deep learning techniques. This study has a classification accuracy of 96.15% using Random Fores, 92.30 using Linear Regression, 96.15% using SVM, and 100% using LSTM. Deep learning methods have been shown to outperform traditional methods in leukemia gene classification by utilizing specific features.https://doi.org/10.1371/journal.pone.0320669 |
| spellingShingle | Mahwish Ilyas Muhammad Ramzan Mohamed Deriche Khalid Mahmood Anam Naz An efficient leukemia prediction method using machine learning and deep learning with selected features. PLoS ONE |
| title | An efficient leukemia prediction method using machine learning and deep learning with selected features. |
| title_full | An efficient leukemia prediction method using machine learning and deep learning with selected features. |
| title_fullStr | An efficient leukemia prediction method using machine learning and deep learning with selected features. |
| title_full_unstemmed | An efficient leukemia prediction method using machine learning and deep learning with selected features. |
| title_short | An efficient leukemia prediction method using machine learning and deep learning with selected features. |
| title_sort | efficient leukemia prediction method using machine learning and deep learning with selected features |
| url | https://doi.org/10.1371/journal.pone.0320669 |
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