Dysregulation of Metabolic Peptides Precedes Hyperinsulinemia and Inflammation Following Exposure to Rotenone in Rats

Dysregulation of Metabolic Peptides Precedes Hyperinsulinemia and Inflammation Following Exposure to Rotenone in Rats

Rotenone, a naturally occurring compound derived from the roots of tropical plants, is used as a broad-spectrum insecticide, piscicide, and pesticide. It is a classical, high-affinity mitochondrial complex I inhibitor that causes not only oxidative stress, α-synuclein phosphorylation, DJ-1 (Parkinso...

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Bibliographic Details
Main Authors: Vandana Zaman, Denise Matzelle, Naren L. Banik, Azizul Haque
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
rotenone
hormonal peptides
inflammation
hyperinsulinemia
obesity
diabetes
Online Access:https://www.mdpi.com/2073-4409/14/2/124
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