The Effect of Perioperative Topical Ketorolac 0.5% on Macular Thickness after Uneventful Phacoemulsification
Background. To evaluate the effects of topical 0.5% ketorolac treatment combined with topical steroids on macular thickness in cases who had uneventful phacoemulsification surgery. Methods. 58 eyes of 58 consecutive cases were included. The mean foveal thickness (MFT), parafoveal thickness (ParaFT),...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/4271671 |
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| author | Derya Dal Ozge Sarac Yasin Toklu Ayse Gul Kocak Altintas Hasan Basri Cakmak Elif Damar Gungor Saban Simsek |
| author_facet | Derya Dal Ozge Sarac Yasin Toklu Ayse Gul Kocak Altintas Hasan Basri Cakmak Elif Damar Gungor Saban Simsek |
| author_sort | Derya Dal |
| collection | DOAJ |
| description | Background. To evaluate the effects of topical 0.5% ketorolac treatment combined with topical steroids on macular thickness in cases who had uneventful phacoemulsification surgery. Methods. 58 eyes of 58 consecutive cases were included. The mean foveal thickness (MFT), parafoveal thickness (ParaFT), and perifoveal thickness (PeriFT) measurements were performed with optical coherence tomography (RTVue-100, Optovue, Fremont, CA, USA) preoperatively and at postoperative 1 week, 1 month, and 2 months. All cases received topical 0.1% dexamethasone postoperatively. Randomly selected cases additionally received topical 0.5% ketorolac, which started 2 days prior to surgery. Cases who received both topical steroids and ketorolac formed group 1 and subjects who received only topical steroids formed group 2. Results. The increase in mean MFT at the 1st week, 1st month, and 2nd months after surgery in group 1 was significantly lower than group 2 (P=0.008, P≤0.001, and P≤0.001, resp.). In group 1, the increase in mean ParaFT and PeriFT was significantly lower than group 2 at the 1st and 2nd months of the surgery (P<0.05 for all variables). Conclusions. Topical ketorolac combined with steroids is highly efficacious in order to prevent increment in thickness on each part of the macula even after an uneventful phacoemulsification surgery comparing to steroid monotheraphy. |
| format | Article |
| id | doaj-art-eb51ed7fc436440b956604f74fa6fc3d |
| institution | DOAJ |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-eb51ed7fc436440b956604f74fa6fc3d2025-08-20T03:21:16ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/42716714271671The Effect of Perioperative Topical Ketorolac 0.5% on Macular Thickness after Uneventful PhacoemulsificationDerya Dal0Ozge Sarac1Yasin Toklu2Ayse Gul Kocak Altintas3Hasan Basri Cakmak4Elif Damar Gungor5Saban Simsek6Department of Ophthalmology, Erzurum Regional Training and Research Hospital, Erzurum, TurkeyDepartment of Ophthalmology, Ankara Ataturk Training and Research Hospital, Faculty of Medicine, Yildirim Beyazit University, Ankara, TurkeyDepartment of Ophthalmology, Ankara Ataturk Training and Research Hospital, Faculty of Medicine, Yildirim Beyazit University, Ankara, TurkeyDepartment of Ophthalmology, Ulucanlar Eye Training and Research Hospital, Ankara, TurkeyDepartment of Ophthalmology, Faculty of Medicine, Hacettepe University, Ankara, TurkeyDepartment of Ophthalmology, Malatya Training and Research Hospital, Malatya, TurkeyDepartment of Ophthalmology, Ankara Ataturk Training and Research Hospital, Faculty of Medicine, Yildirim Beyazit University, Ankara, TurkeyBackground. To evaluate the effects of topical 0.5% ketorolac treatment combined with topical steroids on macular thickness in cases who had uneventful phacoemulsification surgery. Methods. 58 eyes of 58 consecutive cases were included. The mean foveal thickness (MFT), parafoveal thickness (ParaFT), and perifoveal thickness (PeriFT) measurements were performed with optical coherence tomography (RTVue-100, Optovue, Fremont, CA, USA) preoperatively and at postoperative 1 week, 1 month, and 2 months. All cases received topical 0.1% dexamethasone postoperatively. Randomly selected cases additionally received topical 0.5% ketorolac, which started 2 days prior to surgery. Cases who received both topical steroids and ketorolac formed group 1 and subjects who received only topical steroids formed group 2. Results. The increase in mean MFT at the 1st week, 1st month, and 2nd months after surgery in group 1 was significantly lower than group 2 (P=0.008, P≤0.001, and P≤0.001, resp.). In group 1, the increase in mean ParaFT and PeriFT was significantly lower than group 2 at the 1st and 2nd months of the surgery (P<0.05 for all variables). Conclusions. Topical ketorolac combined with steroids is highly efficacious in order to prevent increment in thickness on each part of the macula even after an uneventful phacoemulsification surgery comparing to steroid monotheraphy.http://dx.doi.org/10.1155/2017/4271671 |
| spellingShingle | Derya Dal Ozge Sarac Yasin Toklu Ayse Gul Kocak Altintas Hasan Basri Cakmak Elif Damar Gungor Saban Simsek The Effect of Perioperative Topical Ketorolac 0.5% on Macular Thickness after Uneventful Phacoemulsification Journal of Ophthalmology |
| title | The Effect of Perioperative Topical Ketorolac 0.5% on Macular Thickness after Uneventful Phacoemulsification |
| title_full | The Effect of Perioperative Topical Ketorolac 0.5% on Macular Thickness after Uneventful Phacoemulsification |
| title_fullStr | The Effect of Perioperative Topical Ketorolac 0.5% on Macular Thickness after Uneventful Phacoemulsification |
| title_full_unstemmed | The Effect of Perioperative Topical Ketorolac 0.5% on Macular Thickness after Uneventful Phacoemulsification |
| title_short | The Effect of Perioperative Topical Ketorolac 0.5% on Macular Thickness after Uneventful Phacoemulsification |
| title_sort | effect of perioperative topical ketorolac 0 5 on macular thickness after uneventful phacoemulsification |
| url | http://dx.doi.org/10.1155/2017/4271671 |
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