Epidemiology, Diagnosis, and Management of Cystic Lesions of the Pancreas

Although little is known on the true prevalence of pancreatic cysts, physicians are currently more frequently confronted with pancreatic cysts because of the increasing use of sophisticated cross-sectional abdominal imaging. Cystic lesions of the pancreas comprise of a heterogeneous group of diagnos...

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Main Authors: Koen de Jong, Marco J. Bruno, Paul Fockens
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2012/147465
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author Koen de Jong
Marco J. Bruno
Paul Fockens
author_facet Koen de Jong
Marco J. Bruno
Paul Fockens
author_sort Koen de Jong
collection DOAJ
description Although little is known on the true prevalence of pancreatic cysts, physicians are currently more frequently confronted with pancreatic cysts because of the increasing use of sophisticated cross-sectional abdominal imaging. Cystic lesions of the pancreas comprise of a heterogeneous group of diagnostic entities, some of which are benign such as inflammatory pseudocysts or serous cystadenomas and do not require resection when asymptomatic. Others like mucinous cysts or intraductal papillary mucinous neoplasms (IPMN) have a malignant potential and in these cases surgical resection is often indicated. For this reason an adequate distinction between the various cysts is crucial to optimize management strategy. Different diagnostic methods that could be of value in the differentiation include radiologic imaging techniques such as CT, MR, and endosonography. In addition, fluid aspiration for cytopathology, tumormarkers or molecular analysis is widely used. Different guidelines are available but so far no optimal diagnostic algorithm exists. We summarize the epidemiology, classification, clinical presentation, diagnostics, management, and future perspectives.
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spelling doaj-art-eb4e786bfa2d48b1b24a7d7f3dad39252025-08-20T03:21:18ZengWileyGastroenterology Research and Practice1687-61211687-630X2012-01-01201210.1155/2012/147465147465Epidemiology, Diagnosis, and Management of Cystic Lesions of the PancreasKoen de Jong0Marco J. Bruno1Paul Fockens2Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1100 DE Amsterdam, The NetherlandsDepartment of Gastroenterology and Hepatology, Erasmus Medical Center, 3000 CA, Rotterdam, The NetherlandsDepartment of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1100 DE Amsterdam, The NetherlandsAlthough little is known on the true prevalence of pancreatic cysts, physicians are currently more frequently confronted with pancreatic cysts because of the increasing use of sophisticated cross-sectional abdominal imaging. Cystic lesions of the pancreas comprise of a heterogeneous group of diagnostic entities, some of which are benign such as inflammatory pseudocysts or serous cystadenomas and do not require resection when asymptomatic. Others like mucinous cysts or intraductal papillary mucinous neoplasms (IPMN) have a malignant potential and in these cases surgical resection is often indicated. For this reason an adequate distinction between the various cysts is crucial to optimize management strategy. Different diagnostic methods that could be of value in the differentiation include radiologic imaging techniques such as CT, MR, and endosonography. In addition, fluid aspiration for cytopathology, tumormarkers or molecular analysis is widely used. Different guidelines are available but so far no optimal diagnostic algorithm exists. We summarize the epidemiology, classification, clinical presentation, diagnostics, management, and future perspectives.http://dx.doi.org/10.1155/2012/147465
spellingShingle Koen de Jong
Marco J. Bruno
Paul Fockens
Epidemiology, Diagnosis, and Management of Cystic Lesions of the Pancreas
Gastroenterology Research and Practice
title Epidemiology, Diagnosis, and Management of Cystic Lesions of the Pancreas
title_full Epidemiology, Diagnosis, and Management of Cystic Lesions of the Pancreas
title_fullStr Epidemiology, Diagnosis, and Management of Cystic Lesions of the Pancreas
title_full_unstemmed Epidemiology, Diagnosis, and Management of Cystic Lesions of the Pancreas
title_short Epidemiology, Diagnosis, and Management of Cystic Lesions of the Pancreas
title_sort epidemiology diagnosis and management of cystic lesions of the pancreas
url http://dx.doi.org/10.1155/2012/147465
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