Lymphoproliferative neoplasms and renal cell carcinoma of clear cell type - where is the link?
Introduction. The etiology of higher than expected occurrence of lymphoproliferative neoplasms (LPN) and renal cell carcinoma (RCC) in the same patient has not yet been clarified. Several explanations for this co-occurrence have been postulated: prior cytotoxic treatment, viral infection...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2015-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500054C.pdf |
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| _version_ | 1850163202329935872 |
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| author | Cvetković Zorica Suvajdžić-Vuković Nada Cvetković Bora |
| author_facet | Cvetković Zorica Suvajdžić-Vuković Nada Cvetković Bora |
| author_sort | Cvetković Zorica |
| collection | DOAJ |
| description | Introduction. The etiology of higher than expected occurrence of
lymphoproliferative neoplasms (LPN) and renal cell carcinoma (RCC) in the
same patient has not yet been clarified. Several explanations for this
co-occurrence have been postulated: prior cytotoxic treatment, viral
infections, immunomodulatory effects of tumor itself and shared genetic
and/or environmental factors. Case report. Medical records of 680 consecutive
patients with LPN and 570 consecutive patients with RCC diagnosed between
January 1997 and December 2011 in two centers were retrospectively analyzed.
Co-occurrence of both diseases was registered in five of the patients (3
males, 2 females) and their demographic, clinical and pathological
characteristics were presented. Conclusion. Synchronous occurrence of LPN
neoplasms and RCC or a short latent period between the diagnoses of these two
malignancies in the same patient, as well as the lack of cytotoxic treatment
for firstly occurring neoplasm implies a possible common pathobiology of both
diseases. |
| format | Article |
| id | doaj-art-eb4bb81018e346f48a0c73678765d7ca |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-eb4bb81018e346f48a0c73678765d7ca2025-08-20T02:22:20ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202015-01-0172874074410.2298/VSP140323054C0042-84501500054CLymphoproliferative neoplasms and renal cell carcinoma of clear cell type - where is the link?Cvetković Zorica0Suvajdžić-Vuković Nada1Cvetković Bora2Clinical Hospital Center Zemun, Department of Hematology, BelgradeClinical Center of Serbia, Clinic of Hematology, Belgrade + Faculty of Medicine, BelgradeClinical Hospital Center Zemun, Department of Urology, BelgradeIntroduction. The etiology of higher than expected occurrence of lymphoproliferative neoplasms (LPN) and renal cell carcinoma (RCC) in the same patient has not yet been clarified. Several explanations for this co-occurrence have been postulated: prior cytotoxic treatment, viral infections, immunomodulatory effects of tumor itself and shared genetic and/or environmental factors. Case report. Medical records of 680 consecutive patients with LPN and 570 consecutive patients with RCC diagnosed between January 1997 and December 2011 in two centers were retrospectively analyzed. Co-occurrence of both diseases was registered in five of the patients (3 males, 2 females) and their demographic, clinical and pathological characteristics were presented. Conclusion. Synchronous occurrence of LPN neoplasms and RCC or a short latent period between the diagnoses of these two malignancies in the same patient, as well as the lack of cytotoxic treatment for firstly occurring neoplasm implies a possible common pathobiology of both diseases.http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500054C.pdflymphoproliferative disordersneoplasmskidneynoplasmscomorbidityrisk factorsprognosis |
| spellingShingle | Cvetković Zorica Suvajdžić-Vuković Nada Cvetković Bora Lymphoproliferative neoplasms and renal cell carcinoma of clear cell type - where is the link? Vojnosanitetski Pregled lymphoproliferative disorders neoplasms kidneynoplasms comorbidity risk factors prognosis |
| title | Lymphoproliferative neoplasms and renal cell carcinoma of clear cell type - where is the link? |
| title_full | Lymphoproliferative neoplasms and renal cell carcinoma of clear cell type - where is the link? |
| title_fullStr | Lymphoproliferative neoplasms and renal cell carcinoma of clear cell type - where is the link? |
| title_full_unstemmed | Lymphoproliferative neoplasms and renal cell carcinoma of clear cell type - where is the link? |
| title_short | Lymphoproliferative neoplasms and renal cell carcinoma of clear cell type - where is the link? |
| title_sort | lymphoproliferative neoplasms and renal cell carcinoma of clear cell type where is the link |
| topic | lymphoproliferative disorders neoplasms kidneynoplasms comorbidity risk factors prognosis |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500054C.pdf |
| work_keys_str_mv | AT cvetkoviczorica lymphoproliferativeneoplasmsandrenalcellcarcinomaofclearcelltypewhereisthelink AT suvajdzicvukovicnada lymphoproliferativeneoplasmsandrenalcellcarcinomaofclearcelltypewhereisthelink AT cvetkovicbora lymphoproliferativeneoplasmsandrenalcellcarcinomaofclearcelltypewhereisthelink |