Preventing adverse cardiac events (PACE) in chronic obstructive pulmonary disease (COPD): study protocol for a double-blind, placebo controlled, randomised controlled trial of bisoprolol in COPD

Preventing adverse cardiac events (PACE) in chronic obstructive pulmonary disease (COPD): study protocol for a double-blind, placebo controlled, randomised controlled trial of bisoprolol in COPD

Introduction Heart disease in chronic obstructive pulmonary disease (COPD) is a common but neglected comorbidity. Patients with COPD are frequently excluded from clinical trials of treatments aimed at reducing cardiac morbidity and mortality, which has led to undertreatment of cardiovascular disease...

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Main Authors: Graham S Hillis, Richard Beasley, Claudia C Dobler, Christine Jenkins, Ian A Yang, Jeremy Wrobel, Allison Martin, Robert J Hancox, Belinda Cochrane, Catherina L Chang, Vanessa McDonald, Claude S Farah, Caroline Polak Scowcroft, Ashutosh Aggarwal, Grace Balicki, Shane Galgey
Format: Article
Language:English
Published: BMJ Publishing Group 2021-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/11/8/e053446.full
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