Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory parameters
IntroductionThe aging process is frequently associated with a decline in functional capacity, endurance, muscle quality, and overall quality of life. Examining aging-related biomarkers often requires significant time and financial resources, underscoring the need for a straightforward and practical...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1491584/full |
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| author | Nina Kemala Sari Stepvia Stepvia Muhana Fawwazy Ilyas Siti Setiati Siti Setiati Kuntjoro Harimurti Ika Fitriana |
| author_facet | Nina Kemala Sari Stepvia Stepvia Muhana Fawwazy Ilyas Siti Setiati Siti Setiati Kuntjoro Harimurti Ika Fitriana |
| author_sort | Nina Kemala Sari |
| collection | DOAJ |
| description | IntroductionThe aging process is frequently associated with a decline in functional capacity, endurance, muscle quality, and overall quality of life. Examining aging-related biomarkers often requires significant time and financial resources, underscoring the need for a straightforward and practical indicator. This study aims to investigate the association between handgrip strength and aging-related laboratory parameters in the elderly population of Indonesia.MethodsA cross-sectional study was conducted involving 109 participants aged 60–82 years. Handgrip strength was measured using a Jamar hydraulic hand dynamometer and Jamar PLUS+ digital dynamometer. Aging-related laboratory biomarkers were defined as those indicating physiological aging processes.ResultsThe study revealed a significant association between handgrip strength and several aging-related laboratory parameters, including leukocyte count, absolute neutrophil count, absolute lymphocyte count, neutrophil/lymphocyte ratio, and erythrocyte sedimentation rate.DiscussionThese findings suggest that handgrip strength could serve as a cost-effective, non-invasive predictor of aging-related health status in older adults. Its practical utility highlights its potential for guiding health interventions targeting the elderly population. |
| format | Article |
| id | doaj-art-eb2adac53bd64f2f8bed314c84541457 |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-eb2adac53bd64f2f8bed314c845414572025-01-29T06:46:19ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011210.3389/fmed.2025.14915841491584Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory parametersNina Kemala Sari0Stepvia Stepvia1Muhana Fawwazy Ilyas2Siti Setiati3Siti Setiati4Kuntjoro Harimurti5Ika Fitriana6Geriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, IndonesiaGeriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, IndonesiaFaculty of Medicine, Universitas Sebelas Maret, Surakarta, IndonesiaGeriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, IndonesiaClinical Epidemiology and Evidence-Based Medicine Unit, Dr. Cipto Mangunkusumo National Referral Hospital, Jakarta, IndonesiaGeriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, IndonesiaGeriatric Division, Department of Internal Medicine, Faculty of Medicine, Dr. Cipto Mangunkusumo National Referral Hospital, Universitas Indonesia, Jakarta, IndonesiaIntroductionThe aging process is frequently associated with a decline in functional capacity, endurance, muscle quality, and overall quality of life. Examining aging-related biomarkers often requires significant time and financial resources, underscoring the need for a straightforward and practical indicator. This study aims to investigate the association between handgrip strength and aging-related laboratory parameters in the elderly population of Indonesia.MethodsA cross-sectional study was conducted involving 109 participants aged 60–82 years. Handgrip strength was measured using a Jamar hydraulic hand dynamometer and Jamar PLUS+ digital dynamometer. Aging-related laboratory biomarkers were defined as those indicating physiological aging processes.ResultsThe study revealed a significant association between handgrip strength and several aging-related laboratory parameters, including leukocyte count, absolute neutrophil count, absolute lymphocyte count, neutrophil/lymphocyte ratio, and erythrocyte sedimentation rate.DiscussionThese findings suggest that handgrip strength could serve as a cost-effective, non-invasive predictor of aging-related health status in older adults. Its practical utility highlights its potential for guiding health interventions targeting the elderly population.https://www.frontiersin.org/articles/10.3389/fmed.2025.1491584/fullagingbiomarkerselderly populationfunctional capacityhandgrip strength |
| spellingShingle | Nina Kemala Sari Stepvia Stepvia Muhana Fawwazy Ilyas Siti Setiati Siti Setiati Kuntjoro Harimurti Ika Fitriana Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory parameters Frontiers in Medicine aging biomarkers elderly population functional capacity handgrip strength |
| title | Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory parameters |
| title_full | Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory parameters |
| title_fullStr | Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory parameters |
| title_full_unstemmed | Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory parameters |
| title_short | Handgrip strength as a potential indicator of aging: insights from its association with aging-related laboratory parameters |
| title_sort | handgrip strength as a potential indicator of aging insights from its association with aging related laboratory parameters |
| topic | aging biomarkers elderly population functional capacity handgrip strength |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1491584/full |
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