COVID-19: a vascular nightmare unfolding
The emergence of COVID-19 has been associated with an increased risk of arteriovenous thrombosis, with immune inflammation playing a significant role in the pathogenesis of thrombosis. Numerous drug-related clinical trials have been undertaken to prevent thrombosis, and guidelines for its prevention...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Immunology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1593885/full |
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| author | Qinan Yin Youjin Huang Hulin Wang Yin Wang Xuefei Huang Yujie Song Yueyuan Wang Lizhu Han Bian Yuan |
| author_facet | Qinan Yin Youjin Huang Hulin Wang Yin Wang Xuefei Huang Yujie Song Yueyuan Wang Lizhu Han Bian Yuan |
| author_sort | Qinan Yin |
| collection | DOAJ |
| description | The emergence of COVID-19 has been associated with an increased risk of arteriovenous thrombosis, with immune inflammation playing a significant role in the pathogenesis of thrombosis. Numerous drug-related clinical trials have been undertaken to prevent thrombosis, and guidelines for its prevention and treatment are continuously evolving as our understanding of the disease progresses. This article provides a comprehensive review of the mechanisms underlying thrombosis in COVID-19 patients, as well as the advancements in clinical trials and guidelines for thrombosis prevention with pharmacological interventions. |
| format | Article |
| id | doaj-art-eb25b81f8ede4594a8ad28adefb2b52a |
| institution | Kabale University |
| issn | 1664-3224 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj-art-eb25b81f8ede4594a8ad28adefb2b52a2025-08-20T03:58:18ZengFrontiers Media S.A.Frontiers in Immunology1664-32242025-08-011610.3389/fimmu.2025.15938851593885COVID-19: a vascular nightmare unfoldingQinan Yin0Youjin Huang1Hulin Wang2Yin Wang3Xuefei Huang4Yujie Song5Yueyuan Wang6Lizhu Han7Bian Yuan8Department of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Vascular Surgery Center, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaDepartment of Pharmacy, Personalized Drug Research and Therapy Key Laboratory of Sichuan Province, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaThe emergence of COVID-19 has been associated with an increased risk of arteriovenous thrombosis, with immune inflammation playing a significant role in the pathogenesis of thrombosis. Numerous drug-related clinical trials have been undertaken to prevent thrombosis, and guidelines for its prevention and treatment are continuously evolving as our understanding of the disease progresses. This article provides a comprehensive review of the mechanisms underlying thrombosis in COVID-19 patients, as well as the advancements in clinical trials and guidelines for thrombosis prevention with pharmacological interventions.https://www.frontiersin.org/articles/10.3389/fimmu.2025.1593885/fullCOVID-19thrombosismechanismanticoagulationvaccine |
| spellingShingle | Qinan Yin Youjin Huang Hulin Wang Yin Wang Xuefei Huang Yujie Song Yueyuan Wang Lizhu Han Bian Yuan COVID-19: a vascular nightmare unfolding Frontiers in Immunology COVID-19 thrombosis mechanism anticoagulation vaccine |
| title | COVID-19: a vascular nightmare unfolding |
| title_full | COVID-19: a vascular nightmare unfolding |
| title_fullStr | COVID-19: a vascular nightmare unfolding |
| title_full_unstemmed | COVID-19: a vascular nightmare unfolding |
| title_short | COVID-19: a vascular nightmare unfolding |
| title_sort | covid 19 a vascular nightmare unfolding |
| topic | COVID-19 thrombosis mechanism anticoagulation vaccine |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2025.1593885/full |
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