Radical cystectomy in eldery
Background/Aim. Radical cystectomy is the method of choice for the treatment of muscle invasive bladder cancer. This major surgery is associated with many complications, especially in older patients. The aim of this study was to analyze preoperative comorbidity, and intraoperative and posto...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2015-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501502136B.pdf |
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| author | Bančević Vladimir Aleksić Predrag Milović Novak Spasić Aleksandar Kovačević Božidar Toševski Perica Čampara Zoran Milošević Radovan Cerović Snežana |
| author_facet | Bančević Vladimir Aleksić Predrag Milović Novak Spasić Aleksandar Kovačević Božidar Toševski Perica Čampara Zoran Milošević Radovan Cerović Snežana |
| author_sort | Bančević Vladimir |
| collection | DOAJ |
| description | Background/Aim. Radical cystectomy is the method of choice for the treatment
of muscle invasive bladder cancer. This major surgery is associated with many
complications, especially in older patients. The aim of this study was to
analyze preoperative comorbidity, and intraoperative and postoperative
complicatons in patients older than 75 years. Methods. This clinical,
retrospective study included 46 patients over 75 years, who underwent radical
cystectomy. Indications for surgery, and complications during and after the
surgery were followed up. Results. Preoperatively, anemia caused by hematuria
was registered in 76% of the patients. In 52% of the patients urine
derivation was performed by ileal conduit, in 35% by ureterocutaneostomy and
in 13% orthotopic ileal neobladder was created. The average duration of
surgery was 190 (120-300) min. A total of 76% of the patients were treated by
blood supstitution intraoperatively, average 630 (310-1230) mL. Concerning
pathological stage of transitional cell carcinoma of urinary bladder, 26% of
the patients had T2, 4% T3a, 52% T3b, and 14% T4a stage. In one case,
planocellular carcinoma was diagnosed by patohistological examination, and in
2 cases prostate carcinoma was incidentally found. The average duration of
hospitalization was 16 (8-35) days. Conclusion. The main reason for
cystectomy in patients over 70 and 80 years was gross hematuria caused by
bladder cancer, with consecutive anemia which could not be solved using
endoscopic treatment or blood supstitution. As expected, a prolonged stay in
hospital after cystectomy, and a higher rate of complications were recorded
in this population. |
| format | Article |
| id | doaj-art-eb242317c96d4cc6aec9124ca869156c |
| institution | DOAJ |
| issn | 0042-8450 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-eb242317c96d4cc6aec9124ca869156c2025-08-20T03:06:23ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502015-01-0172213613910.2298/VSP1502136B0042-84501502136BRadical cystectomy in elderyBančević Vladimir0Aleksić Predrag1Milović Novak2Spasić Aleksandar3Kovačević Božidar4Toševski Perica5Čampara Zoran6Milošević Radovan7Cerović Snežana8Military Medical Academy, Clinic of Urology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Clinic of Urology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Clinic of Urology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeMilitary Medical Academy, Clinic of Urology, BelgradeMilitary Medical Academy, Institute of Pathology and Forensic Medicine, BelgradeMilitary Medical Academy, Clinic of Urology, BelgradeMilitary Medical Academy, Clinic of Urology, BelgradeMilitary Medical Academy, Clinic of Urology, Belgrade + University of Defence, Faculty of Medicine of the Military Medical Academy, BelgradeUniversity of Defence, Faculty of Medicine of the Military Medical Academy, Belgrade + Military Medical Academy, Institute of Pathology and Forensic Medicine, BelgradeBackground/Aim. Radical cystectomy is the method of choice for the treatment of muscle invasive bladder cancer. This major surgery is associated with many complications, especially in older patients. The aim of this study was to analyze preoperative comorbidity, and intraoperative and postoperative complicatons in patients older than 75 years. Methods. This clinical, retrospective study included 46 patients over 75 years, who underwent radical cystectomy. Indications for surgery, and complications during and after the surgery were followed up. Results. Preoperatively, anemia caused by hematuria was registered in 76% of the patients. In 52% of the patients urine derivation was performed by ileal conduit, in 35% by ureterocutaneostomy and in 13% orthotopic ileal neobladder was created. The average duration of surgery was 190 (120-300) min. A total of 76% of the patients were treated by blood supstitution intraoperatively, average 630 (310-1230) mL. Concerning pathological stage of transitional cell carcinoma of urinary bladder, 26% of the patients had T2, 4% T3a, 52% T3b, and 14% T4a stage. In one case, planocellular carcinoma was diagnosed by patohistological examination, and in 2 cases prostate carcinoma was incidentally found. The average duration of hospitalization was 16 (8-35) days. Conclusion. The main reason for cystectomy in patients over 70 and 80 years was gross hematuria caused by bladder cancer, with consecutive anemia which could not be solved using endoscopic treatment or blood supstitution. As expected, a prolonged stay in hospital after cystectomy, and a higher rate of complications were recorded in this population.http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501502136B.pdfurinary bladder neoplasmscytectomyagedhematuriacomorbiditypostoperative complications |
| spellingShingle | Bančević Vladimir Aleksić Predrag Milović Novak Spasić Aleksandar Kovačević Božidar Toševski Perica Čampara Zoran Milošević Radovan Cerović Snežana Radical cystectomy in eldery Vojnosanitetski Pregled urinary bladder neoplasms cytectomy aged hematuria comorbidity postoperative complications |
| title | Radical cystectomy in eldery |
| title_full | Radical cystectomy in eldery |
| title_fullStr | Radical cystectomy in eldery |
| title_full_unstemmed | Radical cystectomy in eldery |
| title_short | Radical cystectomy in eldery |
| title_sort | radical cystectomy in eldery |
| topic | urinary bladder neoplasms cytectomy aged hematuria comorbidity postoperative complications |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501502136B.pdf |
| work_keys_str_mv | AT bancevicvladimir radicalcystectomyineldery AT aleksicpredrag radicalcystectomyineldery AT milovicnovak radicalcystectomyineldery AT spasicaleksandar radicalcystectomyineldery AT kovacevicbozidar radicalcystectomyineldery AT tosevskiperica radicalcystectomyineldery AT camparazoran radicalcystectomyineldery AT milosevicradovan radicalcystectomyineldery AT cerovicsnezana radicalcystectomyineldery |