Knockout of TMEM206 in mice associated with a loss of corneal transparency

Knockout of TMEM206 in mice associated with a loss of corneal transparency

AIM: To investigate the role of transmembrane protein 206 (TMEM206) in corneal edema in mice by knockout the TMEM206 gene using CRISPR/Cas9 editing technology. METHODS: TMEM206-knockout mice were generated using the CRISPR-Cas9 system. Variations in ophthalmic pathology were observed using slit lamp...

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Bibliographic Details
Main Authors: Zi-Jian Yang, Shou-Yue Huang, Yu-Feng Zhou, Shun-Chang Sun
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2024-11-01
Series:International Journal of Ophthalmology
Subjects:
transmembrane protein 206
knockout
cornea
edema
mouse
Online Access:http://ies.ijo.cn/en_publish/2024/11/20241101.pdf
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