Research advances of CCR2/MCP-1 and kidney diseases

As a major receptor of monocyte chemotactic protein-1(MCP-1),CC chemokine receptor 2(CCR2)can specifically conjugate to MCP-1,transfer signals into cytoplasm, mediate the chemotaxis and activation of monocytes and macrophages and promote the occurrence and development of inflammation.Previous studie...

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Main Authors: Shen Yan-jie, Yan Li-li, Ren Zhen-hua, Lu Ling, Zhang Qin
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2021-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57904006&Fpath=home&index=0
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author Shen Yan-jie
Yan Li-li
Ren Zhen-hua
Lu Ling
Zhang Qin
author_facet Shen Yan-jie
Yan Li-li
Ren Zhen-hua
Lu Ling
Zhang Qin
author_sort Shen Yan-jie
collection DOAJ
description As a major receptor of monocyte chemotactic protein-1(MCP-1),CC chemokine receptor 2(CCR2)can specifically conjugate to MCP-1,transfer signals into cytoplasm, mediate the chemotaxis and activation of monocytes and macrophages and promote the occurrence and development of inflammation.Previous studies have shown that CCR2/MCP-1 were involved in the development of many kidney diseases.This review summarized the recent research advances of CCR2/MCP-1 and kidney disease.
format Article
id doaj-art-eb1b2ba106ca44ddbcc3b85fb33e560d
institution Kabale University
issn 1671-2390
language zho
publishDate 2021-01-01
publisher Editorial Department of Journal of Clinical Nephrology
record_format Article
series Linchuang shenzangbing zazhi
spelling doaj-art-eb1b2ba106ca44ddbcc3b85fb33e560d2025-08-20T03:48:58ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902021-01-0125726157904006Research advances of CCR2/MCP-1 and kidney diseasesShen Yan-jieYan Li-liRen Zhen-huaLu LingZhang QinAs a major receptor of monocyte chemotactic protein-1(MCP-1),CC chemokine receptor 2(CCR2)can specifically conjugate to MCP-1,transfer signals into cytoplasm, mediate the chemotaxis and activation of monocytes and macrophages and promote the occurrence and development of inflammation.Previous studies have shown that CCR2/MCP-1 were involved in the development of many kidney diseases.This review summarized the recent research advances of CCR2/MCP-1 and kidney disease.http://www.lcszb.com/thesisDetails?columnId=57904006&Fpath=home&index=0CC chemokine receptor 2Monocyte chemotactic protein-1Kidney diseases
spellingShingle Shen Yan-jie
Yan Li-li
Ren Zhen-hua
Lu Ling
Zhang Qin
Research advances of CCR2/MCP-1 and kidney diseases
Linchuang shenzangbing zazhi
CC chemokine receptor 2
Monocyte chemotactic protein-1
Kidney diseases
title Research advances of CCR2/MCP-1 and kidney diseases
title_full Research advances of CCR2/MCP-1 and kidney diseases
title_fullStr Research advances of CCR2/MCP-1 and kidney diseases
title_full_unstemmed Research advances of CCR2/MCP-1 and kidney diseases
title_short Research advances of CCR2/MCP-1 and kidney diseases
title_sort research advances of ccr2 mcp 1 and kidney diseases
topic CC chemokine receptor 2
Monocyte chemotactic protein-1
Kidney diseases
url http://www.lcszb.com/thesisDetails?columnId=57904006&Fpath=home&index=0
work_keys_str_mv AT shenyanjie researchadvancesofccr2mcp1andkidneydiseases
AT yanlili researchadvancesofccr2mcp1andkidneydiseases
AT renzhenhua researchadvancesofccr2mcp1andkidneydiseases
AT luling researchadvancesofccr2mcp1andkidneydiseases
AT zhangqin researchadvancesofccr2mcp1andkidneydiseases