Plasma L-aspartic acid predicts the risk of gastric cancer and modifies the primary prevention effect: a multistage metabolomic profiling and Mendelian randomization study

Plasma L-aspartic acid predicts the risk of gastric cancer and modifies the primary prevention effect: a multistage metabolomic profiling and Mendelian randomization study

Objective: Based on multistage metabolomic profiling and Mendelian randomization analyses, the current study identified plasma metabolites that predicted the risk of developing gastric cancer (GC) and determined whether key metabolite levels modified the GC primary prevention effects. Methods: Plasm...

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Bibliographic Details
Main Authors: Mengyuan Wang, Zhouyi Yin, Hengmin Xu, Zongchao Liu, Sha Huang, Wenhui Wu, Yang Zhang, Tong Zhou, Weicheng You, Kaifeng Pan, Wenqing Li
Format: Article
Language:English
Published: China Anti-Cancer Association 2025-05-01
Series:Cancer Biology & Medicine
Subjects:
gastric cancer
plasma metabolites
mendelian randomization
l-aspartic acid
Online Access:https://www.cancerbiomed.org/content/22/5/525
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