Algae and Type 2 Diabetes: New Treatment Strategies

The review contains recent materials on the effects of extracts, polysaccharides, and polyphenols from brown algae in type 2 diabetes mellitus, which are a potential basis for creating effective antihyperglycemic agents. These biologically active substances are polyvalent biomodulators that have a m...

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Main Authors: N. N. Besednova, S. P. Ermakova, T. A. Kuznetsova, I. D. Makarenkova, S. P. Krizhanovsky, B. G. Andryukov, T. S. Saporozhets
Format: Article
Language:Russian
Published: LLC "Publishing House OKI" 2020-05-01
Series:Антибиотики и Химиотерапия
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Online Access:https://www.antibiotics-chemotherapy.ru/jour/article/view/169
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author N. N. Besednova
S. P. Ermakova
T. A. Kuznetsova
I. D. Makarenkova
S. P. Krizhanovsky
B. G. Andryukov
T. S. Saporozhets
author_facet N. N. Besednova
S. P. Ermakova
T. A. Kuznetsova
I. D. Makarenkova
S. P. Krizhanovsky
B. G. Andryukov
T. S. Saporozhets
author_sort N. N. Besednova
collection DOAJ
description The review contains recent materials on the effects of extracts, polysaccharides, and polyphenols from brown algae in type 2 diabetes mellitus, which are a potential basis for creating effective antihyperglycemic agents. These biologically active substances are polyvalent biomodulators that have a multi-component effect in diabetes. These biopolymers reduce blood glucose levels, increase insulin production, decrease insulin resistance, inhibit α-amylase and α-glucosidase production, have antioxidant and anti-inflammatory activity, protect pancreatic, liver, and kidney tissues from high glucose concentrations. Algae are promising candidates for creating new generation drugs with associated activity, functional foods and dietary supplements for use in type 2 diabetes mellitus.
format Article
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institution Kabale University
issn 0235-2990
language Russian
publishDate 2020-05-01
publisher LLC "Publishing House OKI"
record_format Article
series Антибиотики и Химиотерапия
spelling doaj-art-eb06e93f9ed541f0bc9f8103d047c58c2025-08-20T03:42:02ZrusLLC "Publishing House OKI"Антибиотики и Химиотерапия0235-29902020-05-016411-12546710.1016/0235-2990-2019-64-11-12-54-67168Algae and Type 2 Diabetes: New Treatment StrategiesN. N. Besednova0S. P. Ermakova1T. A. Kuznetsova2I. D. Makarenkova3S. P. Krizhanovsky4B. G. Andryukov5T. S. Saporozhets6Somov Research Institute of Epidemiology and MicrobiologyG. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of SciencesSomov Research Institute of Epidemiology and MicrobiologySomov Research Institute of Epidemiology and MicrobiologyMedical Association of the Far Eastern Branch of the Russian Academy of SciencesSomov Research Institute of Epidemiology and MicrobiologySomov Research Institute of Epidemiology and MicrobiologyThe review contains recent materials on the effects of extracts, polysaccharides, and polyphenols from brown algae in type 2 diabetes mellitus, which are a potential basis for creating effective antihyperglycemic agents. These biologically active substances are polyvalent biomodulators that have a multi-component effect in diabetes. These biopolymers reduce blood glucose levels, increase insulin production, decrease insulin resistance, inhibit α-amylase and α-glucosidase production, have antioxidant and anti-inflammatory activity, protect pancreatic, liver, and kidney tissues from high glucose concentrations. Algae are promising candidates for creating new generation drugs with associated activity, functional foods and dietary supplements for use in type 2 diabetes mellitus.https://www.antibiotics-chemotherapy.ru/jour/article/view/169type 2 diabetessulfated polysaccharidespolyphenolsfucoidanextractsalgae
spellingShingle N. N. Besednova
S. P. Ermakova
T. A. Kuznetsova
I. D. Makarenkova
S. P. Krizhanovsky
B. G. Andryukov
T. S. Saporozhets
Algae and Type 2 Diabetes: New Treatment Strategies
Антибиотики и Химиотерапия
type 2 diabetes
sulfated polysaccharides
polyphenols
fucoidan
extracts
algae
title Algae and Type 2 Diabetes: New Treatment Strategies
title_full Algae and Type 2 Diabetes: New Treatment Strategies
title_fullStr Algae and Type 2 Diabetes: New Treatment Strategies
title_full_unstemmed Algae and Type 2 Diabetes: New Treatment Strategies
title_short Algae and Type 2 Diabetes: New Treatment Strategies
title_sort algae and type 2 diabetes new treatment strategies
topic type 2 diabetes
sulfated polysaccharides
polyphenols
fucoidan
extracts
algae
url https://www.antibiotics-chemotherapy.ru/jour/article/view/169
work_keys_str_mv AT nnbesednova algaeandtype2diabetesnewtreatmentstrategies
AT spermakova algaeandtype2diabetesnewtreatmentstrategies
AT takuznetsova algaeandtype2diabetesnewtreatmentstrategies
AT idmakarenkova algaeandtype2diabetesnewtreatmentstrategies
AT spkrizhanovsky algaeandtype2diabetesnewtreatmentstrategies
AT bgandryukov algaeandtype2diabetesnewtreatmentstrategies
AT tssaporozhets algaeandtype2diabetesnewtreatmentstrategies