Electroacupuncture modulates the gut-brain axis via the PI3K/Akt pathway to improve feeding behavior, body weight, glucolipid metabolism, and reduce insulin resistance in T2DM rats

Electroacupuncture modulates the gut-brain axis via the PI3K/Akt pathway to improve feeding behavior, body weight, glucolipid metabolism, and reduce insulin resistance in T2DM rats

Abstract Background The rising prevalence and high mortality of diabetes have made it a significant public health concern. This study explores how electroacupuncture (EA) influences the PI3K/Akt pathway and its role in regulating the gut-brain axis, focusing on whether EA can modulate this axis via...

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Bibliographic Details
Main Authors: Shaoyang Liu, Shuting Zhuang, Rui Li, Haoru Duan
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Type 2diabetes mellitus
Electroacupuncture
PI3K/Akt pathway
Gut-brain axis
Online Access:https://doi.org/10.1186/s13098-025-01683-y
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