Exploration of Lipid Profile and Wax Ester Content from Local Strain Euglena sp. IDN33 Cultivated in Mixotrophic Condition Combined with Molasses Supplementation

The transition from fossil fuels to sustainable renewable energy is currently growing rapidly. Euglena sp. can be the source of biofuel. Molasses, in addition to Euglena sp., can increase the levels of paramylon and wax esters produced. Therefore, this study aims to analyze cell growth, lipid profi...

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Main Authors: Adam Astiti, Tia Erfianti, Khusnul Qonita Maghfiroh, Renata Adaranyssa Egistha Putri, Eko Agus Suyono
Format: Article
Language:English
Published: Bogor Agricultural University 2025-02-01
Series:Hayati Journal of Biosciences
Online Access:https://journal.ipb.ac.id/index.php/hayati/article/view/58735
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author Adam Astiti
Tia Erfianti
Khusnul Qonita Maghfiroh
Renata Adaranyssa Egistha Putri
Eko Agus Suyono
author_facet Adam Astiti
Tia Erfianti
Khusnul Qonita Maghfiroh
Renata Adaranyssa Egistha Putri
Eko Agus Suyono
author_sort Adam Astiti
collection DOAJ
description The transition from fossil fuels to sustainable renewable energy is currently growing rapidly. Euglena sp. can be the source of biofuel. Molasses, in addition to Euglena sp., can increase the levels of paramylon and wax esters produced. Therefore, this study aims to analyze cell growth, lipid profile, and wax ester content of Euglena sp. cultivated under mixotroph conditions with molasses. Euglena was cultivated under mixotrophic conditions with the addition of various concentrations of molasses (0, 10, 15, and 20 g/L) until the final log phase. Then, measurements were made on cell density, levels of lipids, proteins, and paramylon to measure the growth and metabolites profile of Euglena sp., along with lipid profile and wax ester analysis using GC-MS. The results of the study showed that 10 g/L molasses increased Euglena growth (SGR 0.1736± 0.0213 mg/ml) and carbohydrate (0.426 mg/ml) but reduced lipid accumulation (2.29 mg/ml). This treatment provides the best result before control. Molasses does not increase carbohydrates and protein but increases paramylon accumulation. The GC-MS assay detected more lipid profiles and concentrations of each lipid type in non-molasses-treated Euglena sp. compared to molasses-treated. Euglena was cultivated on molasses, which was dominated by palmitic acid and myristyl myristate with the absence of PUFA-type fatty acids in the cells, while the untreated ones were dominated by stearic acid and myristyl myristate. Thus, 10 g/L supplementation of molasses is the most effective treatment compared to others.
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publishDate 2025-02-01
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spelling doaj-art-eafb548d4a9046e5be6eed65b95cee9f2025-08-20T03:11:33ZengBogor Agricultural UniversityHayati Journal of Biosciences1978-30192086-40942025-02-0132310.4308/hjb.32.3.805-818Exploration of Lipid Profile and Wax Ester Content from Local Strain Euglena sp. IDN33 Cultivated in Mixotrophic Condition Combined with Molasses SupplementationAdam Astiti0Tia Erfianti1Khusnul Qonita Maghfiroh2Renata Adaranyssa Egistha Putri3Eko Agus Suyono4Laboratory of Biotechnology Faculty of Biology, Universitas Gadjah Mada, Yogyakarta 55281, IndonesiaLaboratory of Biotechnology Faculty of Biology, Universitas Gadjah Mada, Yogyakarta 55281, IndonesiaLaboratory of Biotechnology Faculty of Biology, Universitas Gadjah Mada, Yogyakarta 55281, IndonesiaStudy Program of Biotechnology, Graduate School of Universitas Gadjah Mada, Yogyakarta 55281, IndonesiaLaboratory of Biotechnology Faculty of Biology, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia The transition from fossil fuels to sustainable renewable energy is currently growing rapidly. Euglena sp. can be the source of biofuel. Molasses, in addition to Euglena sp., can increase the levels of paramylon and wax esters produced. Therefore, this study aims to analyze cell growth, lipid profile, and wax ester content of Euglena sp. cultivated under mixotroph conditions with molasses. Euglena was cultivated under mixotrophic conditions with the addition of various concentrations of molasses (0, 10, 15, and 20 g/L) until the final log phase. Then, measurements were made on cell density, levels of lipids, proteins, and paramylon to measure the growth and metabolites profile of Euglena sp., along with lipid profile and wax ester analysis using GC-MS. The results of the study showed that 10 g/L molasses increased Euglena growth (SGR 0.1736± 0.0213 mg/ml) and carbohydrate (0.426 mg/ml) but reduced lipid accumulation (2.29 mg/ml). This treatment provides the best result before control. Molasses does not increase carbohydrates and protein but increases paramylon accumulation. The GC-MS assay detected more lipid profiles and concentrations of each lipid type in non-molasses-treated Euglena sp. compared to molasses-treated. Euglena was cultivated on molasses, which was dominated by palmitic acid and myristyl myristate with the absence of PUFA-type fatty acids in the cells, while the untreated ones were dominated by stearic acid and myristyl myristate. Thus, 10 g/L supplementation of molasses is the most effective treatment compared to others. https://journal.ipb.ac.id/index.php/hayati/article/view/58735
spellingShingle Adam Astiti
Tia Erfianti
Khusnul Qonita Maghfiroh
Renata Adaranyssa Egistha Putri
Eko Agus Suyono
Exploration of Lipid Profile and Wax Ester Content from Local Strain Euglena sp. IDN33 Cultivated in Mixotrophic Condition Combined with Molasses Supplementation
Hayati Journal of Biosciences
title Exploration of Lipid Profile and Wax Ester Content from Local Strain Euglena sp. IDN33 Cultivated in Mixotrophic Condition Combined with Molasses Supplementation
title_full Exploration of Lipid Profile and Wax Ester Content from Local Strain Euglena sp. IDN33 Cultivated in Mixotrophic Condition Combined with Molasses Supplementation
title_fullStr Exploration of Lipid Profile and Wax Ester Content from Local Strain Euglena sp. IDN33 Cultivated in Mixotrophic Condition Combined with Molasses Supplementation
title_full_unstemmed Exploration of Lipid Profile and Wax Ester Content from Local Strain Euglena sp. IDN33 Cultivated in Mixotrophic Condition Combined with Molasses Supplementation
title_short Exploration of Lipid Profile and Wax Ester Content from Local Strain Euglena sp. IDN33 Cultivated in Mixotrophic Condition Combined with Molasses Supplementation
title_sort exploration of lipid profile and wax ester content from local strain euglena sp idn33 cultivated in mixotrophic condition combined with molasses supplementation
url https://journal.ipb.ac.id/index.php/hayati/article/view/58735
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AT khusnulqonitamaghfiroh explorationoflipidprofileandwaxestercontentfromlocalstraineuglenaspidn33cultivatedinmixotrophicconditioncombinedwithmolassessupplementation
AT renataadaranyssaegisthaputri explorationoflipidprofileandwaxestercontentfromlocalstraineuglenaspidn33cultivatedinmixotrophicconditioncombinedwithmolassessupplementation
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