Antagonising Yin Yang 1 ameliorates the symptoms of lupus nephritis via modulating T lymphocyte signaling

Antagonising Yin Yang 1 ameliorates the symptoms of lupus nephritis via modulating T lymphocyte signaling

Lupus nephritis (LN) is a chronic complication of systemic lupus erythematosus (SLE). At present, no drugs are capable of delaying the progression of LN without a risk of serious side effects. There is thus a pressing need for further studies of LN pathogenesis to identify novel therapeutic targets...

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Bibliographic Details
Main Authors: Haoxing Yuan, Zheng Peng, Meilian Zhang, Honglian Li, Kunyu Lu, Chan Yang, Minmin Li, Shuwen Liu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Pharmacological Research
Subjects:
Lupus nephritis
Yin Yang 1 (YY1)
T lymphocyte
Drug screen
Rebamipide
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824004705
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