Multiclassification of Colorectal Polyps from Colonoscopy Images Using AI for Early Diagnosis

<b>Background/Objectives:</b> Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, emphasizing the critical need for the accurate classification of precancerous polyps. This research presents an extensive analysis of the multiclassification fra...

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Main Authors: Jothiraj Selvaraj, Kishwar Sadaf, Shabnam Mohamed Aslam, Snekhalatha Umapathy
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Diagnostics
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Online Access:https://www.mdpi.com/2075-4418/15/10/1285
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author Jothiraj Selvaraj
Kishwar Sadaf
Shabnam Mohamed Aslam
Snekhalatha Umapathy
author_facet Jothiraj Selvaraj
Kishwar Sadaf
Shabnam Mohamed Aslam
Snekhalatha Umapathy
author_sort Jothiraj Selvaraj
collection DOAJ
description <b>Background/Objectives:</b> Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, emphasizing the critical need for the accurate classification of precancerous polyps. This research presents an extensive analysis of the multiclassification framework leveraging various deep learning (DL) architectures for the automated classification of colorectal polyps from colonoscopy images. <b>Methods:</b> The proposed methodology integrates real-time data for training and utilizes a publicly available dataset for testing, ensuring generalizability. The real-time images were cautiously annotated and verified by a panel of experts, including post-graduate medical doctors and gastroenterology specialists. The DL models were designed to categorize the preprocessed colonoscopy images into four clinically significant classes: hyperplastic, serrated, adenoma, and normal. A suite of state-of-the-art models, including VGG16, VGG19, ResNet50, DenseNet121, EfficientNetV2, InceptionNetV3, Vision Transformer (ViT), and the custom-developed CRP-ViT, were trained and rigorously evaluated for this task. <b>Results:</b> Notably, the CRP-ViT model exhibited superior capability in capturing intricate features, achieving an impressive accuracy of 97.28% during training and 96.02% during validation with real-time images. Furthermore, the model demonstrated remarkable performance during testing on the public dataset, attaining an accuracy of 95.69%. To facilitate real-time interaction and clinical applicability, a user-friendly interface was developed using Gradio, allowing healthcare professionals to upload colonoscopy images and receive instant classification results. <b>Conclusions:</b> The CRP-ViT model effectively predicts and categorizes colonoscopy images into clinically relevant classes, aiding gastroenterologists in decision-making. This study highlights the potential of integrating AI-driven models into routine clinical practice to improve colorectal cancer screening outcomes and reduce diagnostic variability.
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spelling doaj-art-eaf20cd2c3c64b3ba7f1f3cf2e4d42a32025-08-20T01:56:31ZengMDPI AGDiagnostics2075-44182025-05-011510128510.3390/diagnostics15101285Multiclassification of Colorectal Polyps from Colonoscopy Images Using AI for Early DiagnosisJothiraj Selvaraj0Kishwar Sadaf1Shabnam Mohamed Aslam2Snekhalatha Umapathy3Department of Biomedical Engineering, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu 603203, IndiaDepartment of Computer Science, College of Computer and Information Sciences, Majmaah University, Al Majmaah 11952, Saudi ArabiaDepartment of Information Technology, College of Computer and Information Sciences, Majmaah University, Al Majmaah 11952, Saudi ArabiaDepartment of Biomedical Engineering, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu 603203, India<b>Background/Objectives:</b> Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, emphasizing the critical need for the accurate classification of precancerous polyps. This research presents an extensive analysis of the multiclassification framework leveraging various deep learning (DL) architectures for the automated classification of colorectal polyps from colonoscopy images. <b>Methods:</b> The proposed methodology integrates real-time data for training and utilizes a publicly available dataset for testing, ensuring generalizability. The real-time images were cautiously annotated and verified by a panel of experts, including post-graduate medical doctors and gastroenterology specialists. The DL models were designed to categorize the preprocessed colonoscopy images into four clinically significant classes: hyperplastic, serrated, adenoma, and normal. A suite of state-of-the-art models, including VGG16, VGG19, ResNet50, DenseNet121, EfficientNetV2, InceptionNetV3, Vision Transformer (ViT), and the custom-developed CRP-ViT, were trained and rigorously evaluated for this task. <b>Results:</b> Notably, the CRP-ViT model exhibited superior capability in capturing intricate features, achieving an impressive accuracy of 97.28% during training and 96.02% during validation with real-time images. Furthermore, the model demonstrated remarkable performance during testing on the public dataset, attaining an accuracy of 95.69%. To facilitate real-time interaction and clinical applicability, a user-friendly interface was developed using Gradio, allowing healthcare professionals to upload colonoscopy images and receive instant classification results. <b>Conclusions:</b> The CRP-ViT model effectively predicts and categorizes colonoscopy images into clinically relevant classes, aiding gastroenterologists in decision-making. This study highlights the potential of integrating AI-driven models into routine clinical practice to improve colorectal cancer screening outcomes and reduce diagnostic variability.https://www.mdpi.com/2075-4418/15/10/1285colorectal cancercolorectal polypCRP-ViTmulticlassificationcolonoscopy images
spellingShingle Jothiraj Selvaraj
Kishwar Sadaf
Shabnam Mohamed Aslam
Snekhalatha Umapathy
Multiclassification of Colorectal Polyps from Colonoscopy Images Using AI for Early Diagnosis
Diagnostics
colorectal cancer
colorectal polyp
CRP-ViT
multiclassification
colonoscopy images
title Multiclassification of Colorectal Polyps from Colonoscopy Images Using AI for Early Diagnosis
title_full Multiclassification of Colorectal Polyps from Colonoscopy Images Using AI for Early Diagnosis
title_fullStr Multiclassification of Colorectal Polyps from Colonoscopy Images Using AI for Early Diagnosis
title_full_unstemmed Multiclassification of Colorectal Polyps from Colonoscopy Images Using AI for Early Diagnosis
title_short Multiclassification of Colorectal Polyps from Colonoscopy Images Using AI for Early Diagnosis
title_sort multiclassification of colorectal polyps from colonoscopy images using ai for early diagnosis
topic colorectal cancer
colorectal polyp
CRP-ViT
multiclassification
colonoscopy images
url https://www.mdpi.com/2075-4418/15/10/1285
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AT shabnammohamedaslam multiclassificationofcolorectalpolypsfromcolonoscopyimagesusingaiforearlydiagnosis
AT snekhalathaumapathy multiclassificationofcolorectalpolypsfromcolonoscopyimagesusingaiforearlydiagnosis