Brain age as an imaging-based diagnostic and treatment biomarker of neurodegenerative disorders

In the proposed project, we expect to improve diagnosis and treatment for patients suffering from neurodegenerative diseases by establishing a new biomarker based on deep learning and big data outputs. We will use brain age, a neuroimaging-derived marker of brain health which has previously rarely b...

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Main Author: Max Korbmacher
Format: Article
Language:English
Published: Pensoft Publishers 2025-05-01
Series:Research Ideas and Outcomes
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Online Access:https://riojournal.com/article/156738/download/pdf/
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author Max Korbmacher
author_facet Max Korbmacher
author_sort Max Korbmacher
collection DOAJ
description In the proposed project, we expect to improve diagnosis and treatment for patients suffering from neurodegenerative diseases by establishing a new biomarker based on deep learning and big data outputs. We will use brain age, a neuroimaging-derived marker of brain health which has previously rarely been tested longitudinally, but not in neurodegenerative disorders. The analyses will help to assess treatment response as well as stratifying and sub-typing neurodegenerative disease, based on brain structural characteristics in addition to multiple other markers of disease expression.
format Article
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issn 2367-7163
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series Research Ideas and Outcomes
spelling doaj-art-eaf1821044a04dc8b5a8ef22f046a08a2025-08-20T02:30:56ZengPensoft PublishersResearch Ideas and Outcomes2367-71632025-05-011111310.3897/rio.11.e156738156738Brain age as an imaging-based diagnostic and treatment biomarker of neurodegenerative disordersMax Korbmacher0Western Norway University of Applied SciencesIn the proposed project, we expect to improve diagnosis and treatment for patients suffering from neurodegenerative diseases by establishing a new biomarker based on deep learning and big data outputs. We will use brain age, a neuroimaging-derived marker of brain health which has previously rarely been tested longitudinally, but not in neurodegenerative disorders. The analyses will help to assess treatment response as well as stratifying and sub-typing neurodegenerative disease, based on brain structural characteristics in addition to multiple other markers of disease expression.https://riojournal.com/article/156738/download/pdf/magnetic resonance imagingneurodegenerative diso
spellingShingle Max Korbmacher
Brain age as an imaging-based diagnostic and treatment biomarker of neurodegenerative disorders
Research Ideas and Outcomes
magnetic resonance imaging
neurodegenerative diso
title Brain age as an imaging-based diagnostic and treatment biomarker of neurodegenerative disorders
title_full Brain age as an imaging-based diagnostic and treatment biomarker of neurodegenerative disorders
title_fullStr Brain age as an imaging-based diagnostic and treatment biomarker of neurodegenerative disorders
title_full_unstemmed Brain age as an imaging-based diagnostic and treatment biomarker of neurodegenerative disorders
title_short Brain age as an imaging-based diagnostic and treatment biomarker of neurodegenerative disorders
title_sort brain age as an imaging based diagnostic and treatment biomarker of neurodegenerative disorders
topic magnetic resonance imaging
neurodegenerative diso
url https://riojournal.com/article/156738/download/pdf/
work_keys_str_mv AT maxkorbmacher brainageasanimagingbaseddiagnosticandtreatmentbiomarkerofneurodegenerativedisorders