Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1β and IL-1ra production in multiple sclerosis

Interleukin (IL)-1 gene polymorphisms: relevance of disease severity associated alleles with IL-1β and IL-1ra production in multiple sclerosis

Background: Multiple sclerosis (MS) is an autoimmune disorder, with a considerable genetic influence on susceptibility and disease course. Cytokines play an important role in MS pathophysiology, and genes encoding various cytokines are logical candidates to assess possible associations with MS susce...

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Bibliographic Details
Main Authors: Hans M. Schrijver, Jaco van As, J. Bart A. Crusius, Christien D. Dijkstra, Bernard M. J. Uitdehaag
Format: Article
Language:English
Published: Wiley 2003-01-01
Series:Mediators of Inflammation
Subjects:
Genetics
Interleukin-1
Interleukin-1 receptor antagonist
Multiple sclerosis
Cytokines.
Online Access:http://dx.doi.org/10.1080/0962933031000097691
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