Integrated network toxicology, machine learning and molecular docking reveal the mechanism of benzopyrene-induced periodontitis

Abstract Background Environmental pollutants, particularly from air pollution and tobacco smoke, have emerged as significant risk factors. Benzopyrene (BaP), a Group 1 carcinogen, is ubiquitously present in these pollutants, yet its molecular mechanisms in periodontitis remain largely unexplored. Me...

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Bibliographic Details
Main Authors: Wen Wenjie, Li Rui, Zhuo Pengpeng, Deng Chao, Zhang Donglin
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s40360-025-00961-9
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