Investigating the potential mechanism of microneedling in alopecia areata mice based on 16S rRNA sequencing and metabolomics

Investigating the potential mechanism of microneedling in alopecia areata mice based on 16S rRNA sequencing and metabolomics

BackgroundThe present study investigates the relationship between alopecia areata (AA) and intestinal microecology, examining the effect of microneedling on the microecology of alopecia areata.MethodsAn animal model of AA was established using imiquimod-induced C3H/HeJ mice. Halometasone was applied...

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Bibliographic Details
Main Authors: Yue Zhang, Lu Li, Lei Cao, Rushan Xia
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Microbiology
Subjects:
alopecia areata
microneedling
gut microbes
16S rRNA sequencing
short-chain fatty acids
intestinal microecology
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1649496/full
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