Peroxidation of n-3 Polyunsaturated Fatty Acids Inhibits the Induction of iNOS Gene Expression in Proinflammatory Cytokine-Stimulated Hepatocytes

Peroxidation of n-3 Polyunsaturated Fatty Acids Inhibits the Induction of iNOS Gene Expression in Proinflammatory Cytokine-Stimulated Hepatocytes

Eicosapentaenoic acid and docosahexaenoic acid (EPA/DHA), n-3 polyunsaturated fatty acids (PUFAs), have a variety of biological activities including anti-inflammatory and anticancer effects. We hypothesized that their peroxidized products contributed in part to anti-inflammatory effects. In the live...

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Bibliographic Details
Main Authors: Yoshiro Araki, Miho Matsumiya, Takashi Matsuura, Masaharu Oishi, Masaki Kaibori, Tadayoshi Okumura, Mikio Nishizawa, Hideho Takada, A-Hon Kwon
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Journal of Nutrition and Metabolism
Online Access:http://dx.doi.org/10.1155/2011/374542
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