Synthesis of L-cysteine-CdSe Quantum Dots for optical Biosensing Application

Cadmium selenide (CdSe) nanocrystals, modified with water-soluble L-cysteine and known as CdSe/Cys nanocrystals, were synthesized using L-cysteine as a stabilizing agent. This synthesis process ensured the formation of highly stable nanocrystals with desirable properties for various applications. T...

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Main Authors: Thalfaa Rasheed Ajeel, Manal Midhat Abdullah, Fadhel Mohammed Lafta
Format: Article
Language:English
Published: University of Baghdad 2025-06-01
Series:Iraqi Journal of Physics
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Online Access:https://ijp.uobaghdad.edu.iq/index.php/physics/article/view/1336
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author Thalfaa Rasheed Ajeel
Manal Midhat Abdullah
Fadhel Mohammed Lafta
author_facet Thalfaa Rasheed Ajeel
Manal Midhat Abdullah
Fadhel Mohammed Lafta
author_sort Thalfaa Rasheed Ajeel
collection DOAJ
description Cadmium selenide (CdSe) nanocrystals, modified with water-soluble L-cysteine and known as CdSe/Cys nanocrystals, were synthesized using L-cysteine as a stabilizing agent. This synthesis process ensured the formation of highly stable nanocrystals with desirable properties for various applications. The CdSe/Cys nanocrystals were carefully studied using advanced methods to understand their structure, composition, and optical features in detail. The peak that shows the preferred (111) orientation of L-cysteine-capped CdSe matches the usual core components, as indicated by the XRD pattern. On the other hand, the peaks at (220) and (311) are not as prominent. Photoluminescence (PL) spectroscopy was conducted to study the optical properties of the CdSe/Cys nanocrystals. The PL spectra's strong fluorescence emission showed these nanocrystals' excellent quantum efficiency. The emission peak was sharp and well-defined, highlighting the uniformity in size and composition of the synthesised nanocrystals. The study revealed the robust fluorescence of the spherical CdSe/Cys nanoparticles, with an average diameter of 2.3 nm. Modifying the surface of CdSe nanoparticles with cysteine improved their water solubility and biocompatibility.
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publishDate 2025-06-01
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spelling doaj-art-eae1682e2fec49dbbe4bf8aabea373dc2025-08-20T02:06:22ZengUniversity of BaghdadIraqi Journal of Physics2070-40032664-55482025-06-0123210.30723/ijp.v23i2.1336Synthesis of L-cysteine-CdSe Quantum Dots for optical Biosensing ApplicationThalfaa Rasheed Ajeel0https://orcid.org/0009-0003-3730-6724Manal Midhat Abdullah1Fadhel Mohammed Lafta2Department of Physics, College of Science, University of Baghdad, Baghdad, IraqDepartment of Physics, College of Science, University of Baghdad, Baghdad, IraqDepartment of Biology, College of Science, University of Baghdad, Baghdad, Iraq Cadmium selenide (CdSe) nanocrystals, modified with water-soluble L-cysteine and known as CdSe/Cys nanocrystals, were synthesized using L-cysteine as a stabilizing agent. This synthesis process ensured the formation of highly stable nanocrystals with desirable properties for various applications. The CdSe/Cys nanocrystals were carefully studied using advanced methods to understand their structure, composition, and optical features in detail. The peak that shows the preferred (111) orientation of L-cysteine-capped CdSe matches the usual core components, as indicated by the XRD pattern. On the other hand, the peaks at (220) and (311) are not as prominent. Photoluminescence (PL) spectroscopy was conducted to study the optical properties of the CdSe/Cys nanocrystals. The PL spectra's strong fluorescence emission showed these nanocrystals' excellent quantum efficiency. The emission peak was sharp and well-defined, highlighting the uniformity in size and composition of the synthesised nanocrystals. The study revealed the robust fluorescence of the spherical CdSe/Cys nanoparticles, with an average diameter of 2.3 nm. Modifying the surface of CdSe nanoparticles with cysteine improved their water solubility and biocompatibility. https://ijp.uobaghdad.edu.iq/index.php/physics/article/view/1336CdSe Quantum DotsL-cysteineBiosensorsNanomaterialsOptical Properties
spellingShingle Thalfaa Rasheed Ajeel
Manal Midhat Abdullah
Fadhel Mohammed Lafta
Synthesis of L-cysteine-CdSe Quantum Dots for optical Biosensing Application
Iraqi Journal of Physics
CdSe Quantum Dots
L-cysteine
Biosensors
Nanomaterials
Optical Properties
title Synthesis of L-cysteine-CdSe Quantum Dots for optical Biosensing Application
title_full Synthesis of L-cysteine-CdSe Quantum Dots for optical Biosensing Application
title_fullStr Synthesis of L-cysteine-CdSe Quantum Dots for optical Biosensing Application
title_full_unstemmed Synthesis of L-cysteine-CdSe Quantum Dots for optical Biosensing Application
title_short Synthesis of L-cysteine-CdSe Quantum Dots for optical Biosensing Application
title_sort synthesis of l cysteine cdse quantum dots for optical biosensing application
topic CdSe Quantum Dots
L-cysteine
Biosensors
Nanomaterials
Optical Properties
url https://ijp.uobaghdad.edu.iq/index.php/physics/article/view/1336
work_keys_str_mv AT thalfaarasheedajeel synthesisoflcysteinecdsequantumdotsforopticalbiosensingapplication
AT manalmidhatabdullah synthesisoflcysteinecdsequantumdotsforopticalbiosensingapplication
AT fadhelmohammedlafta synthesisoflcysteinecdsequantumdotsforopticalbiosensingapplication