Epidemiology and Pathogenesis of Coronavirus Disease (COVID-19)
An acute respiratory syndrome (ARDS) episode was first identified in Wuhan, China, and later officially designated as COVID-19 by the WHO. It is caused by SARS-CoV-2 that is likely associated with zoonotic transmission. Based on the live data from live reference website Worldometer which provides...
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| Format: | Article |
| Language: | English |
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ResearchersLinks, Ltd
2020-04-01
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| Series: | Novel Research in Microbiology Journal |
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| Online Access: | https://nrmj.journals.ekb.eg/article_84016_16555c248016ee3da6a4d4873e93ba89.pdf |
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| _version_ | 1850227683189850112 |
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| author | Ram Bahadur Khadka Ravin Bhandari Rabin Gyawali Balram Neupane Dhakaraj Pant |
| author_facet | Ram Bahadur Khadka Ravin Bhandari Rabin Gyawali Balram Neupane Dhakaraj Pant |
| author_sort | Ram Bahadur Khadka |
| collection | DOAJ |
| description | An acute respiratory syndrome (ARDS) episode was first identified in Wuhan, China, and later officially
designated as COVID-19 by the WHO. It is caused by SARS-CoV-2 that is likely associated with zoonotic
transmission. Based on the live data from live reference website Worldometer which provides counters and realtime statistics for diverse topics data, COVID-19 has influenced 186 nations. China reported 25% of cases, while
75% of the remaining cases were reported in other nations. The clinical and genetic characteristics of SARSCoV-2 support the similar pathogenesis pattern between SARS-CoV and MERS-CoV. The elevated level of
cytokine release during the infection caused the failure of multiple organs leading to the patient death. Treatment
of patients depends on the clinical course and symptoms associated with the COVID-19. Several prevention and
control measures including; active surveillance, use of masks, and hand sanitizers are recommended to stop the
spread of this virus. Besides, COVID-19 was sampled using a throat swab to detect the viral nucleic acid using
Real Time Polymerase Chain Reaction (RT-PCR), for early detection and treatments evaluation. In this review,
we comprehensively summarized the COVID-19 epidemiology, pathogenesis and diagnosis, using suitable
literatures obtained from reliable sources. |
| format | Article |
| id | doaj-art-eae0c47779b84ec99a0e7f042e541446 |
| institution | OA Journals |
| issn | 2537-0286 2537-0294 |
| language | English |
| publishDate | 2020-04-01 |
| publisher | ResearchersLinks, Ltd |
| record_format | Article |
| series | Novel Research in Microbiology Journal |
| spelling | doaj-art-eae0c47779b84ec99a0e7f042e5414462025-08-20T02:04:44ZengResearchersLinks, LtdNovel Research in Microbiology Journal2537-02862537-02942020-04-014267568710.21608/nrmj.2020.84016Epidemiology and Pathogenesis of Coronavirus Disease (COVID-19)Ram Bahadur Khadka0Ravin Bhandari1Rabin Gyawali2Balram Neupane3Dhakaraj Pant4Department of Laboratory Sciences, Faculty of Health Science, Crimson College of Technology affiliated to Pokhara University, Devinagar-11, Butwal, NepalDepartment of Pharmacy, Faculty of Health Science, Crimson College of Technology affiliated to Pokhara University, Devinagar-11, Butwal, NepalDepartment of Basic Science, NSIHS, DJNC, Nepal1Department of Laboratory Sciences, Faculty of Health Science, Crimson College of Technology affiliated to Pokhara University, Devinagar-11, Butwal, NepalDepartment of Laboratory Sciences, Faculty of Health Science, Pokhara University, Dhungepatan, NepalAn acute respiratory syndrome (ARDS) episode was first identified in Wuhan, China, and later officially designated as COVID-19 by the WHO. It is caused by SARS-CoV-2 that is likely associated with zoonotic transmission. Based on the live data from live reference website Worldometer which provides counters and realtime statistics for diverse topics data, COVID-19 has influenced 186 nations. China reported 25% of cases, while 75% of the remaining cases were reported in other nations. The clinical and genetic characteristics of SARSCoV-2 support the similar pathogenesis pattern between SARS-CoV and MERS-CoV. The elevated level of cytokine release during the infection caused the failure of multiple organs leading to the patient death. Treatment of patients depends on the clinical course and symptoms associated with the COVID-19. Several prevention and control measures including; active surveillance, use of masks, and hand sanitizers are recommended to stop the spread of this virus. Besides, COVID-19 was sampled using a throat swab to detect the viral nucleic acid using Real Time Polymerase Chain Reaction (RT-PCR), for early detection and treatments evaluation. In this review, we comprehensively summarized the COVID-19 epidemiology, pathogenesis and diagnosis, using suitable literatures obtained from reliable sources.https://nrmj.journals.ekb.eg/article_84016_16555c248016ee3da6a4d4873e93ba89.pdfcoronaviruscovid-19sars-cov-2mers-covpathogenesisepidemiology |
| spellingShingle | Ram Bahadur Khadka Ravin Bhandari Rabin Gyawali Balram Neupane Dhakaraj Pant Epidemiology and Pathogenesis of Coronavirus Disease (COVID-19) Novel Research in Microbiology Journal coronavirus covid-19 sars-cov-2 mers-cov pathogenesis epidemiology |
| title | Epidemiology and Pathogenesis of Coronavirus Disease (COVID-19) |
| title_full | Epidemiology and Pathogenesis of Coronavirus Disease (COVID-19) |
| title_fullStr | Epidemiology and Pathogenesis of Coronavirus Disease (COVID-19) |
| title_full_unstemmed | Epidemiology and Pathogenesis of Coronavirus Disease (COVID-19) |
| title_short | Epidemiology and Pathogenesis of Coronavirus Disease (COVID-19) |
| title_sort | epidemiology and pathogenesis of coronavirus disease covid 19 |
| topic | coronavirus covid-19 sars-cov-2 mers-cov pathogenesis epidemiology |
| url | https://nrmj.journals.ekb.eg/article_84016_16555c248016ee3da6a4d4873e93ba89.pdf |
| work_keys_str_mv | AT rambahadurkhadka epidemiologyandpathogenesisofcoronavirusdiseasecovid19 AT ravinbhandari epidemiologyandpathogenesisofcoronavirusdiseasecovid19 AT rabingyawali epidemiologyandpathogenesisofcoronavirusdiseasecovid19 AT balramneupane epidemiologyandpathogenesisofcoronavirusdiseasecovid19 AT dhakarajpant epidemiologyandpathogenesisofcoronavirusdiseasecovid19 |