Association of Abnormal Renal Profiles with Subretinal Fluid in Diabetic Macular Edema
Purpose. To investigate the risk factors for subretinal fluid (SRF) in diabetic macular edema (DME). Methods. We reviewed the records of 66 patients with DME. Systemic parameters, including hypertension, glycosylated hemoglobin, serum fasting glucose, total cholesterol, triglycerides, and diabetic k...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2022/5581679 |
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| author | Xiaoyan Zhang Xiaofeng Hao Linan Wang Like Xie |
| author_facet | Xiaoyan Zhang Xiaofeng Hao Linan Wang Like Xie |
| author_sort | Xiaoyan Zhang |
| collection | DOAJ |
| description | Purpose. To investigate the risk factors for subretinal fluid (SRF) in diabetic macular edema (DME). Methods. We reviewed the records of 66 patients with DME. Systemic parameters, including hypertension, glycosylated hemoglobin, serum fasting glucose, total cholesterol, triglycerides, and diabetic kidney disease, were evaluated. Renal parameters for diabetic kidney disease included serum albumin, serum creatinine, albuminuria, and estimated glomerular filtration rate. Ocular factors included visual acuity and diabetic retinopathy, and the following parameters are evaluated through optical coherence tomography examination: disorganization of the retinal inner layers, loss of ellipsoid zone, central subretinal fluid thickness, central macular thickness, and presence of SRF. Results. Higher albuminuria (odds ratio, 3.431; 95% confidence interval, 1.039–11.334; P=0.043) was associated with the presence of SRF in patients with DME. Lower serum albumin levels (beta = −14.028, se = 6.646, P=0.044) were associated with increased SRF thickness. Conclusions. Poor kidney function was associated with the presence of SRF in DME. Screening for SRF in DME in patients with higher albuminuria and lower serum albumin levels should be routinely performed. |
| format | Article |
| id | doaj-art-eada48a7f4e040b4a7f6892443d6e0d6 |
| institution | DOAJ |
| issn | 2090-0058 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-eada48a7f4e040b4a7f6892443d6e0d62025-08-20T03:21:10ZengWileyJournal of Ophthalmology2090-00582022-01-01202210.1155/2022/5581679Association of Abnormal Renal Profiles with Subretinal Fluid in Diabetic Macular EdemaXiaoyan Zhang0Xiaofeng Hao1Linan Wang2Like Xie3Department of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyDepartment of OphthalmologyPurpose. To investigate the risk factors for subretinal fluid (SRF) in diabetic macular edema (DME). Methods. We reviewed the records of 66 patients with DME. Systemic parameters, including hypertension, glycosylated hemoglobin, serum fasting glucose, total cholesterol, triglycerides, and diabetic kidney disease, were evaluated. Renal parameters for diabetic kidney disease included serum albumin, serum creatinine, albuminuria, and estimated glomerular filtration rate. Ocular factors included visual acuity and diabetic retinopathy, and the following parameters are evaluated through optical coherence tomography examination: disorganization of the retinal inner layers, loss of ellipsoid zone, central subretinal fluid thickness, central macular thickness, and presence of SRF. Results. Higher albuminuria (odds ratio, 3.431; 95% confidence interval, 1.039–11.334; P=0.043) was associated with the presence of SRF in patients with DME. Lower serum albumin levels (beta = −14.028, se = 6.646, P=0.044) were associated with increased SRF thickness. Conclusions. Poor kidney function was associated with the presence of SRF in DME. Screening for SRF in DME in patients with higher albuminuria and lower serum albumin levels should be routinely performed.http://dx.doi.org/10.1155/2022/5581679 |
| spellingShingle | Xiaoyan Zhang Xiaofeng Hao Linan Wang Like Xie Association of Abnormal Renal Profiles with Subretinal Fluid in Diabetic Macular Edema Journal of Ophthalmology |
| title | Association of Abnormal Renal Profiles with Subretinal Fluid in Diabetic Macular Edema |
| title_full | Association of Abnormal Renal Profiles with Subretinal Fluid in Diabetic Macular Edema |
| title_fullStr | Association of Abnormal Renal Profiles with Subretinal Fluid in Diabetic Macular Edema |
| title_full_unstemmed | Association of Abnormal Renal Profiles with Subretinal Fluid in Diabetic Macular Edema |
| title_short | Association of Abnormal Renal Profiles with Subretinal Fluid in Diabetic Macular Edema |
| title_sort | association of abnormal renal profiles with subretinal fluid in diabetic macular edema |
| url | http://dx.doi.org/10.1155/2022/5581679 |
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