Bilateral Vocal Cord Paralysis and Cervicolumbar Radiculopathy as the Presenting Paraneoplastic Manifestations of Small Cell Lung Cancer: A Case Report and Literature Review
Introduction. Bilateral vocal cord paralysis (BVCP) is a potential medical emergency. The Otolaryngologist plays a crucial role in the diagnosis and management of BVCP and must consider a broad differential diagnosis. We present a rare case of BVCP secondary to anti-Hu paraneoplastic syndrome. Case...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2016/2868190 |
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| author | Jeffrey C. Yeung C. Elizabeth Pringle Harmanjatinder S. Sekhon Shaun J. Kilty Kristian Macdonald |
| author_facet | Jeffrey C. Yeung C. Elizabeth Pringle Harmanjatinder S. Sekhon Shaun J. Kilty Kristian Macdonald |
| author_sort | Jeffrey C. Yeung |
| collection | DOAJ |
| description | Introduction. Bilateral vocal cord paralysis (BVCP) is a potential medical emergency. The Otolaryngologist plays a crucial role in the diagnosis and management of BVCP and must consider a broad differential diagnosis. We present a rare case of BVCP secondary to anti-Hu paraneoplastic syndrome. Case Presentation. A 58-year-old female presented to an Otolaryngology clinic with a history of progressive hoarseness and dysphagia. Flexible nasolaryngoscopy demonstrated BVCP. Cross-sectional imaging of the brain and vagus nerves was negative. An antiparaneoplastic antibody panel was positive for anti-Hu antibodies. This led to an endobronchial biopsy of a paratracheal lymph node, which confirmed the diagnosis of small cell lung cancer. Conclusion. Paraneoplastic neuropathy is a rare cause of BVCP and should be considered when more common pathologies are ruled out. This is the second reported case of BVCP as a presenting symptom of paraneoplastic syndrome secondary to small cell lung cancer. |
| format | Article |
| id | doaj-art-ead8a8621ad0419686f2946518e16232 |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-ead8a8621ad0419686f2946518e162322025-02-03T01:33:26ZengWileyCase Reports in Otolaryngology2090-67652090-67732016-01-01201610.1155/2016/28681902868190Bilateral Vocal Cord Paralysis and Cervicolumbar Radiculopathy as the Presenting Paraneoplastic Manifestations of Small Cell Lung Cancer: A Case Report and Literature ReviewJeffrey C. Yeung0C. Elizabeth Pringle1Harmanjatinder S. Sekhon2Shaun J. Kilty3Kristian Macdonald4Department of Otolaryngology-Head & Neck Surgery, University of Ottawa, Ottawa, ON, CanadaDivision of Neurology, Department of Medicine, University of Ottawa, Ottawa, ON, CanadaDepartment of Pathology & Laboratory Medicine, University of Ottawa, Ottawa, ON, CanadaDepartment of Otolaryngology-Head & Neck Surgery, University of Ottawa, Ottawa, ON, CanadaDepartment of Otolaryngology-Head & Neck Surgery, University of Ottawa, Ottawa, ON, CanadaIntroduction. Bilateral vocal cord paralysis (BVCP) is a potential medical emergency. The Otolaryngologist plays a crucial role in the diagnosis and management of BVCP and must consider a broad differential diagnosis. We present a rare case of BVCP secondary to anti-Hu paraneoplastic syndrome. Case Presentation. A 58-year-old female presented to an Otolaryngology clinic with a history of progressive hoarseness and dysphagia. Flexible nasolaryngoscopy demonstrated BVCP. Cross-sectional imaging of the brain and vagus nerves was negative. An antiparaneoplastic antibody panel was positive for anti-Hu antibodies. This led to an endobronchial biopsy of a paratracheal lymph node, which confirmed the diagnosis of small cell lung cancer. Conclusion. Paraneoplastic neuropathy is a rare cause of BVCP and should be considered when more common pathologies are ruled out. This is the second reported case of BVCP as a presenting symptom of paraneoplastic syndrome secondary to small cell lung cancer.http://dx.doi.org/10.1155/2016/2868190 |
| spellingShingle | Jeffrey C. Yeung C. Elizabeth Pringle Harmanjatinder S. Sekhon Shaun J. Kilty Kristian Macdonald Bilateral Vocal Cord Paralysis and Cervicolumbar Radiculopathy as the Presenting Paraneoplastic Manifestations of Small Cell Lung Cancer: A Case Report and Literature Review Case Reports in Otolaryngology |
| title | Bilateral Vocal Cord Paralysis and Cervicolumbar Radiculopathy as the Presenting Paraneoplastic Manifestations of Small Cell Lung Cancer: A Case Report and Literature Review |
| title_full | Bilateral Vocal Cord Paralysis and Cervicolumbar Radiculopathy as the Presenting Paraneoplastic Manifestations of Small Cell Lung Cancer: A Case Report and Literature Review |
| title_fullStr | Bilateral Vocal Cord Paralysis and Cervicolumbar Radiculopathy as the Presenting Paraneoplastic Manifestations of Small Cell Lung Cancer: A Case Report and Literature Review |
| title_full_unstemmed | Bilateral Vocal Cord Paralysis and Cervicolumbar Radiculopathy as the Presenting Paraneoplastic Manifestations of Small Cell Lung Cancer: A Case Report and Literature Review |
| title_short | Bilateral Vocal Cord Paralysis and Cervicolumbar Radiculopathy as the Presenting Paraneoplastic Manifestations of Small Cell Lung Cancer: A Case Report and Literature Review |
| title_sort | bilateral vocal cord paralysis and cervicolumbar radiculopathy as the presenting paraneoplastic manifestations of small cell lung cancer a case report and literature review |
| url | http://dx.doi.org/10.1155/2016/2868190 |
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