New Discoveries in Enantiomeric Separation of Racemic Tofisopam

Resolution process of tofisopam has been re-evaluated now based on our new investigations. Originally, it was carried out in the water-chloroform system, where the intermediate salt of high diastereomeric excess was described as (R)-TOF·(R,R)-DBTA·(H2O)3. Opposed to previous assumptions, we have act...

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Bibliographic Details
Main Authors: Miklós Hunor Bosits, Emese Pálovics, János Madarász, Elemér Fogassy
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2019/4980792
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